Detailed information of TA system TA080282

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 20735..21260
• Replicon: plasmid pQJDsal2
• Accession: NZ_CP022965
• Organism: Salmonella enterica subsp. enterica serovar Pullorum strain QJ-2D-Sal

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: I3W3D5
• Locus tag: CJD41_RS24500
• Protein ID: WP_001159863.1
• Coordinates: 20735..21040 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: M7S5D0
• Locus tag: CJD41_RS24505
• Protein ID: WP_000813641.1
• Coordinates: 21042..21260 (-)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CJD41_RS24460	16114..16674	-	561	WP_071785580.1	inverse autotransporter beta domain-containing protein	-
CJD41_RS24465	17394..17879	-	486	WP_000905606.1	membrane protein	-
CJD41_RS24470	17873..18382	-	510	WP_001576634.1	CaiF/GrlA family transcriptional regulator	-
CJD41_RS24480	18386..19099	-	714	Protein_20	EAL domain-containing protein	-
CJD41_RS24485	19108..19890	-	783	WP_000082169.1	site-specific integrase	-
CJD41_RS24490	19925..20446	-	522	WP_000198608.1	hypothetical protein	-
CJD41_RS24495	20443..20733	-	291	WP_001266176.1	hypothetical protein	-
CJD41_RS24500	20735..21040	-	306	WP_001159863.1	type II toxin-antitoxin system toxin CcdB	Toxin
CJD41_RS24505	21042..21260	-	219	WP_000813641.1	type II toxin-antitoxin system antitoxin CcdA	Antitoxin
CJD41_RS24510	22005..22235	+	231	WP_001261283.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
CJD41_RS24515	22232..22660	+	429	WP_001746752.1	type II toxin-antitoxin system VapC family toxin	-
CJD41_RS24530	23230..24078	-	849	WP_000175397.1	SdiA-regulated domain-containing protein	-
CJD41_RS25130	24104..24265	-	162	WP_001816720.1	hypothetical protein	-
CJD41_RS24535	24526..24738	-	213	WP_000063791.1	hypothetical protein	-
CJD41_RS24540	24811..25395	-	585	WP_024138406.1	hypothetical protein	-
CJD41_RS24550	25520..26233	-	714	WP_000801114.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..86369	86369

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 15030.03 Da
• Isoelectric Point: 5.5500

>T80282 WP_001159863.1 NZ_CP022965:c21040-20735 [Salmonella enterica subsp. enterica serovar Pullorum]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 306 bp

>T80282 NZ_CP022965:c21040-20735 [Salmonella enterica subsp. enterica serovar Pullorum]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 10761.91 Da
• Isoelectric Point: 5.5500

>AT80282 WP_000813641.1 NZ_CP022965:c21260-21042 [Salmonella enterica subsp. enterica serovar Pullorum]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 219 bp

>AT80282 NZ_CP022965:c21260-21042 [Salmonella enterica subsp. enterica serovar Pullorum]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Structures

Toxin

• AlphaFold DB: I3W3D5

Antitoxin

• AlphaFold DB: A0A656ICA6