80275

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1766488..1767296 Replicon chromosome
Accession NZ_CP022961
Organism Plantactinospora sp. KBS50

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag CIK06_RS07995 Protein ID WP_095564295.1
Coordinates 1766775..1767296 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag CIK06_RS07990 Protein ID WP_095567480.1
Coordinates 1766488..1766778 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIK06_RS07990 1766488..1766778 + 291 WP_095567480.1 DUF1778 domain-containing protein Antitoxin
CIK06_RS07995 1766775..1767296 + 522 WP_095564295.1 GNAT family N-acetyltransferase Toxin
CIK06_RS29185 1767486..1767821 + 336 WP_157756646.1 hypothetical protein -
CIK06_RS08005 1768566..1768730 - 165 Protein_1581 GntR family transcriptional regulator -
CIK06_RS29190 1768940..1769215 + 276 WP_198348134.1 hypothetical protein -
CIK06_RS29195 1769209..1769694 + 486 WP_157756648.1 hypothetical protein -
CIK06_RS08010 1770427..1771518 - 1092 WP_157756649.1 hypothetical protein -
CIK06_RS08015 1771658..1771876 + 219 WP_095567655.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(58-146)

Antitoxin

Vibrio phage ICP1, Orf50

(3-83)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 18556.38 Da        Isoelectric Point: 9.5318

>T80275 WP_095564295.1 NZ_CP022961:1766775-1767296 [Plantactinospora sp. KBS50]
VSSRFSSVEPLSAMHVVTGFDCGSPAQSVWLAEHALQAHRAGLSRVYVVADADHPDRRVIGYYALAAGSVAPADASPRLR
QGAGRYHQPVVILTRLGVDRSAQGAGLGRALVVDVLRRIAAAAEVIGVRAVLIHCETDAARDFYLRLAKFEPSPTDPMHL
LLLMKDLRRALAG

Download         Length: 522 bp

>T80275 NZ_CP022961:1766775-1767296 [Plantactinospora sp. KBS50]
GTGAGTTCGCGTTTCTCGTCGGTCGAGCCGTTGTCGGCCATGCATGTGGTGACCGGCTTCGACTGCGGCTCGCCTGCTCA
GTCGGTCTGGCTGGCCGAGCACGCCCTGCAGGCGCACCGGGCCGGGCTGTCCCGGGTGTACGTCGTCGCTGACGCCGATC
ACCCGGATCGCCGGGTGATCGGCTATTACGCCCTGGCTGCCGGCAGCGTCGCCCCGGCTGACGCCTCCCCACGGCTGCGG
CAGGGTGCCGGCCGCTACCACCAGCCCGTGGTGATCCTGACCCGCCTCGGCGTCGACCGCAGCGCCCAGGGCGCCGGACT
CGGACGTGCCCTGGTGGTTGATGTGCTGCGGCGCATCGCCGCCGCAGCCGAGGTCATCGGTGTCCGCGCGGTGCTCATCC
ACTGCGAGACCGACGCCGCCCGCGACTTCTATCTGCGCCTGGCCAAGTTCGAGCCGAGTCCCACGGATCCGATGCACCTG
CTGCTGTTGATGAAGGACCTCCGCCGAGCTCTCGCGGGGTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10202.50 Da        Isoelectric Point: 4.6437

>AT80275 WP_095567480.1 NZ_CP022961:1766488-1766778 [Plantactinospora sp. KBS50]
MSAKAERLHLRVDAEQKALLEAASQAAGASVSTFVLKAATDAAADVLADRRAFLLDEAAWRVFDEALDRPAQDVAGLREL
VAGPTVLDRSAGEVQR

Download         Length: 291 bp

>AT80275 NZ_CP022961:1766488-1766778 [Plantactinospora sp. KBS50]
ATGAGTGCGAAGGCGGAGCGGCTACACCTACGGGTGGATGCCGAACAGAAGGCGTTGCTGGAGGCGGCCAGCCAGGCCGC
CGGTGCGAGTGTGTCGACGTTCGTACTGAAGGCGGCCACCGACGCGGCGGCTGACGTGCTCGCCGATCGGCGAGCGTTCC
TGCTGGACGAGGCCGCGTGGCGGGTGTTCGACGAGGCGCTGGACCGCCCGGCCCAGGATGTTGCCGGTCTGCGCGAGTTG
GTGGCTGGGCCGACGGTTCTGGACCGCTCGGCGGGCGAGGTGCAGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References