Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 332850..333658 Replicon chromosome
Accession NZ_CP022961
Organism Plantactinospora sp. KBS50

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag CIK06_RS01515 Protein ID WP_095563299.1
Coordinates 333137..333658 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag CIK06_RS01510 Protein ID WP_095567480.1
Coordinates 332850..333140 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIK06_RS01500 328416..330821 - 2406 WP_157756561.1 hypothetical protein -
CIK06_RS01505 331082..332008 + 927 WP_095563298.1 hypothetical protein -
CIK06_RS01510 332850..333140 + 291 WP_095567480.1 DUF1778 domain-containing protein Antitoxin
CIK06_RS01515 333137..333658 + 522 WP_095563299.1 GNAT family N-acetyltransferase Toxin
CIK06_RS29045 333896..334222 - 327 WP_157756562.1 hypothetical protein -
CIK06_RS29050 334212..334658 + 447 WP_157756563.1 hypothetical protein -
CIK06_RS01520 335135..336358 + 1224 WP_095563300.1 proteinase inhibitor I4 serpin -
CIK06_RS01525 336621..337772 + 1152 WP_198348071.1 lytic polysaccharide monooxygenase -
CIK06_RS01530 337839..338315 - 477 WP_095567482.1 type II toxin-antitoxin system PemK/MazF family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(3-83)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 18586.36 Da        Isoelectric Point: 9.0696

>T80274 WP_095563299.1 NZ_CP022961:333137-333658 [Plantactinospora sp. KBS50]
VSSRFSSVEPLSAMHVVTGFDCGSPAQSVWLAEHALQAHRAGLSRVYVVADADHPDRRVIGYYALAAGSVAPADASPRLR
QGAGRYHQPVVILTRLGVDRSAQDAGLGRALVVDALRRIAAAAEVIGVRAVLIHCETDAARDFYLRLAKFEPSPTDPMHL
LLLMKDLRRALAG

Download         Length: 522 bp

>T80274 NZ_CP022961:333137-333658 [Plantactinospora sp. KBS50]
GTGAGTTCGCGTTTCTCGTCGGTCGAGCCGTTGTCGGCCATGCATGTGGTGACCGGCTTCGACTGCGGCTCGCCTGCTCA
GTCGGTCTGGCTGGCCGAGCACGCCCTGCAGGCGCACCGGGCCGGGCTGTCCCGGGTGTACGTCGTCGCTGACGCCGATC
ACCCGGATCGCCGGGTGATCGGCTATTACGCCCTGGCTGCCGGCAGCGTCGCCCCGGCTGACGCCTCCCCACGGCTGCGG
CAGGGTGCCGGCCGCTACCACCAGCCCGTGGTGATCCTGACCCGCCTCGGCGTCGACCGCAGCGCCCAGGACGCCGGACT
CGGACGTGCCCTGGTGGTTGATGCGCTGCGGCGCATCGCCGCCGCAGCCGAGGTCATCGGTGTCCGCGCGGTGCTCATCC
ACTGCGAGACCGACGCCGCCCGCGACTTCTATCTGCGCCTGGCCAAGTTCGAGCCGAGTCCCACGGATCCGATGCACCTG
CTGCTGTTGATGAAGGACCTCCGCCGAGCTCTCGCGGGGTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10202.50 Da        Isoelectric Point: 4.6437

>AT80274 WP_095567480.1 NZ_CP022961:332850-333140 [Plantactinospora sp. KBS50]
MSAKAERLHLRVDAEQKALLEAASQAAGASVSTFVLKAATDAAADVLADRRAFLLDEAAWRVFDEALDRPAQDVAGLREL
VAGPTVLDRSAGEVQR

Download         Length: 291 bp

>AT80274 NZ_CP022961:332850-333140 [Plantactinospora sp. KBS50]
ATGAGTGCGAAGGCGGAGCGGCTACACCTACGGGTGGATGCCGAACAGAAGGCGTTGCTGGAGGCGGCCAGCCAGGCCGC
CGGTGCGAGTGTGTCGACGTTCGTACTGAAGGCGGCCACCGACGCGGCGGCTGACGTGCTCGCCGATCGGCGAGCGTTCC
TGCTGGACGAGGCCGCGTGGCGGGTGTTCGACGAGGCGCTGGACCGCCCGGCCCAGGATGTTGCCGGTCTGCGCGAGTTG
GTGGCTGGGCCGACGGTTCTGGACCGCTCGGCGGGCGAGGTGCAGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References