Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1960146..1960291 Replicon chromosome
Accession NZ_CP022924
Organism Klebsiella pneumoniae strain ST307PT01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1960182..1960284 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1960146..1960291 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJ258_RS09775 1955276..1957336 + 2061 WP_004148850.1 oligopeptidase B -
CJ258_RS09780 1957340..1957999 - 660 WP_032435029.1 exodeoxyribonuclease X -
CJ258_RS09785 1958078..1958308 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CJ258_RS09790 1958421..1958795 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CJ258_RS09795 1958799..1959668 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
CJ258_RS09800 1959685..1960023 + 339 WP_002911404.1 YebY family protein -
- 1960146..1960291 - 146 - - Antitoxin
- 1960182..1960284 + 103 - - Toxin
CJ258_RS28510 1960659..1960802 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CJ258_RS09810 1960907..1961875 - 969 WP_004151446.1 VirK/YbjX family protein -
CJ258_RS09815 1962032..1962685 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
CJ258_RS09820 1962682..1962873 - 192 WP_002911395.1 YebW family protein -
CJ258_RS09825 1962971..1963210 - 240 WP_002911393.1 YebV family protein -
CJ258_RS09830 1963326..1964759 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T80225 NZ_CP022924:1960182-1960284 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT80225 NZ_CP022924:c1960291-1960146 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References