Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1959417..1959562 Replicon chromosome
Accession NZ_CP022922
Organism Klebsiella pneumoniae strain ST307PT02

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1959453..1959555 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1959417..1959562 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJ259_RS09785 1954547..1956607 + 2061 WP_004148850.1 oligopeptidase B -
CJ259_RS09790 1956611..1957270 - 660 WP_032435029.1 exodeoxyribonuclease X -
CJ259_RS09795 1957349..1957579 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CJ259_RS09800 1957692..1958066 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CJ259_RS09805 1958070..1958939 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
CJ259_RS09810 1958956..1959294 + 339 WP_002911404.1 YebY family protein -
- 1959417..1959562 - 146 - - Antitoxin
- 1959453..1959555 + 103 - - Toxin
CJ259_RS28235 1959930..1960073 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CJ259_RS09820 1960178..1961146 - 969 WP_004151446.1 VirK/YbjX family protein -
CJ259_RS09825 1961303..1961956 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
CJ259_RS09830 1961953..1962144 - 192 WP_002911395.1 YebW family protein -
CJ259_RS09835 1962242..1962481 - 240 WP_002911393.1 YebV family protein -
CJ259_RS09840 1962597..1964030 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T80204 NZ_CP022922:1959453-1959555 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT80204 NZ_CP022922:c1959562-1959417 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References