Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1959415..1959560 Replicon chromosome
Accession NZ_CP022916
Organism Klebsiella pneumoniae strain ST307PT04

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1959451..1959553 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1959415..1959560 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJ257_RS09775 1954545..1956605 + 2061 WP_004148850.1 oligopeptidase B -
CJ257_RS09780 1956609..1957268 - 660 WP_032435029.1 exodeoxyribonuclease X -
CJ257_RS09785 1957347..1957577 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CJ257_RS09790 1957690..1958064 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CJ257_RS09795 1958068..1958937 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
CJ257_RS09800 1958954..1959292 + 339 WP_002911404.1 YebY family protein -
- 1959415..1959560 - 146 - - Antitoxin
- 1959451..1959553 + 103 - - Toxin
CJ257_RS28325 1959928..1960071 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CJ257_RS09810 1960176..1961144 - 969 WP_004151446.1 VirK/YbjX family protein -
CJ257_RS09815 1961301..1961954 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
CJ257_RS09820 1961951..1962142 - 192 WP_002911395.1 YebW family protein -
CJ257_RS09825 1962240..1962479 - 240 WP_002911393.1 YebV family protein -
CJ257_RS09830 1962595..1964028 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T80162 NZ_CP022916:1959451-1959553 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT80162 NZ_CP022916:c1959560-1959415 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References