Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-Phd |
Location | 142341..142906 | Replicon | chromosome |
Accession | NZ_CP022915 | ||
Organism | Rhodococcus pyridinivorans strain GF3 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | CJU69_RS00665 | Protein ID | WP_024102981.1 |
Coordinates | 142341..142619 (-) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | CJU69_RS00670 | Protein ID | WP_006551856.1 |
Coordinates | 142616..142906 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CJU69_RS00635 | 137459..138178 | + | 720 | WP_019290045.1 | 2OG-Fe(II) oxygenase | - |
CJU69_RS00640 | 138215..139186 | - | 972 | WP_006551850.1 | phosphotriesterase | - |
CJU69_RS00645 | 139231..140061 | - | 831 | WP_094979475.1 | SDR family oxidoreductase | - |
CJU69_RS00650 | 140182..140844 | + | 663 | WP_094979476.1 | alpha-ketoglutarate-dependent dioxygenase AlkB | - |
CJU69_RS00655 | 140994..141746 | + | 753 | WP_064060432.1 | cutinase family protein | - |
CJU69_RS00660 | 141805..142284 | + | 480 | WP_006551854.1 | MarR family transcriptional regulator | - |
CJU69_RS00665 | 142341..142619 | - | 279 | WP_024102981.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CJU69_RS00670 | 142616..142906 | - | 291 | WP_006551856.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
CJU69_RS00675 | 143120..143938 | - | 819 | WP_094979477.1 | bacteriocin family protein | - |
CJU69_RS00680 | 143935..144963 | - | 1029 | WP_024102977.1 | Dyp-type peroxidase | - |
CJU69_RS00685 | 145040..146641 | - | 1602 | WP_094979478.1 | L-lactate permease | - |
CJU69_RS00690 | 146646..147074 | - | 429 | WP_094979479.1 | HIT family protein | - |
CJU69_RS00695 | 147071..147673 | - | 603 | WP_019290064.1 | TetR/AcrR family transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10268.82 Da Isoelectric Point: 10.2002
>T80156 WP_024102981.1 NZ_CP022915:c142619-142341 [Rhodococcus pyridinivorans]
MSTPDHPYRLVMARSAARAMARSLPEKVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVE
VTAISHRADAYR
MSTPDHPYRLVMARSAARAMARSLPEKVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVE
VTAISHRADAYR
Download Length: 279 bp
>T80156 NZ_CP022915:c142619-142341 [Rhodococcus pyridinivorans]
ATGAGCACTCCGGACCACCCGTATCGGCTGGTGATGGCGAGGTCGGCTGCACGCGCCATGGCGAGGTCGTTGCCGGAGAA
AGTAGCAACTGCGGTATACGAGTTCGTCACAGGACCCCTTCTCGAGAATCCGAAGCGGGTGGGGAAGCCGTTGAATCCGC
CTCTTGCGCCGGCGTACAGCGCCCGGCGAGGTGAATATCGCGTCCTGTATCTGATCGATGATGCGAACCGCACGGTCGAG
GTCACCGCGATCTCGCACCGTGCCGATGCGTATCGATAG
ATGAGCACTCCGGACCACCCGTATCGGCTGGTGATGGCGAGGTCGGCTGCACGCGCCATGGCGAGGTCGTTGCCGGAGAA
AGTAGCAACTGCGGTATACGAGTTCGTCACAGGACCCCTTCTCGAGAATCCGAAGCGGGTGGGGAAGCCGTTGAATCCGC
CTCTTGCGCCGGCGTACAGCGCCCGGCGAGGTGAATATCGCGTCCTGTATCTGATCGATGATGCGAACCGCACGGTCGAG
GTCACCGCGATCTCGCACCGTGCCGATGCGTATCGATAG
Antitoxin
Download Length: 97 a.a. Molecular weight: 10788.92 Da Isoelectric Point: 4.2336
>AT80156 WP_006551856.1 NZ_CP022915:c142906-142616 [Rhodococcus pyridinivorans]
MYMTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVD
VQELTQLMRDARSSEE
MYMTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVD
VQELTQLMRDARSSEE
Download Length: 291 bp
>AT80156 NZ_CP022915:c142906-142616 [Rhodococcus pyridinivorans]
ATGTACATGACGACTCTTCCTGTTGCCGACGCGCGGGCGCAATTGTCACGACTGGTCGATGAGGCCGAGCGCACACACGA
GCGATTCGAGATCACCCGCAACGGGCACCGCGCCGCGGTGCTTCTCGGTGCCGACGATTACGACGCGATGCAGGAGACGA
TCGCGGTGTTGTCGGATACGGATCTGCTGCGGGCGCACGTCGAGGGCCGAACGGAGGTCGAGTCGGGAGACGTCGTCGAT
GTACAGGAATTGACGCAGCTGATGCGTGATGCTCGGTCGTCCGAGGAATGA
ATGTACATGACGACTCTTCCTGTTGCCGACGCGCGGGCGCAATTGTCACGACTGGTCGATGAGGCCGAGCGCACACACGA
GCGATTCGAGATCACCCGCAACGGGCACCGCGCCGCGGTGCTTCTCGGTGCCGACGATTACGACGCGATGCAGGAGACGA
TCGCGGTGTTGTCGGATACGGATCTGCTGCGGGCGCACGTCGAGGGCCGAACGGAGGTCGAGTCGGGAGACGTCGTCGAT
GTACAGGAATTGACGCAGCTGATGCGTGATGCTCGGTCGTCCGAGGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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