Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 1908226..1908688 Replicon chromosome
Accession NZ_CP022881
Organism Staphylococcus sp. M0911

Toxin (Protein)


Gene name TsaT Uniprot ID -
Locus tag ssp1_RS09215 Protein ID WP_002450868.1
Coordinates 1908503..1908688 (+) Length 62 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID -
Locus tag ssp1_RS09210 Protein ID WP_002450867.1
Coordinates 1908226..1908483 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ssp1_RS09170 1903480..1903803 + 324 WP_075778052.1 thioredoxin family protein -
ssp1_RS09175 1903912..1904451 - 540 WP_075778051.1 nitroreductase -
ssp1_RS09180 1904529..1905245 - 717 WP_075778050.1 type I 3-dehydroquinate dehydratase -
ssp1_RS09185 1905423..1905845 + 423 WP_002450862.1 organic hydroperoxide resistance protein -
ssp1_RS09190 1906128..1906622 + 495 WP_002450863.1 GNAT family N-acetyltransferase -
ssp1_RS09195 1906752..1907342 - 591 WP_075778048.1 histidine phosphatase family protein -
ssp1_RS09200 1907543..1907776 + 234 WP_002450865.1 hypothetical protein -
ssp1_RS09205 1907768..1907971 - 204 WP_002450866.1 sterile alpha motif-like domain-containing protein -
ssp1_RS09210 1908226..1908483 + 258 WP_002450867.1 hypothetical protein Antitoxin
ssp1_RS09215 1908503..1908688 + 186 WP_002450868.1 hypothetical protein Toxin
ssp1_RS09220 1908788..1909369 + 582 WP_075778047.1 hypothetical protein -
ssp1_RS09225 1909429..1909662 - 234 WP_002450870.1 hypothetical protein -
ssp1_RS09230 1909926..1910678 + 753 WP_049424894.1 poly-gamma-glutamate hydrolase family protein -
ssp1_RS09235 1910768..1911052 + 285 WP_075778045.1 hypothetical protein -
ssp1_RS09245 1911812..1912051 + 240 WP_002450874.1 hypothetical protein -
ssp1_RS09250 1912280..1912513 + 234 WP_075778044.1 hypothetical protein -
ssp1_RS09255 1912687..1912887 - 201 WP_002450876.1 cold-shock protein -
ssp1_RS09260 1913207..1913572 - 366 WP_075778589.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(149-401)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-69)


Sequences

Toxin        


Download         Length: 62 a.a.        Molecular weight: 6991.71 Da        Isoelectric Point: 10.1605

>T79830 WP_002450868.1 NZ_CP022881:1908503-1908688 [Staphylococcus sp. M0911]
MSLHFTILFWLSLIFIIAGAIILAIMLKTKKESKKESYLGFTIVFFIFGLAMLIYTLLFGL

Download         Length: 186 bp

>T79830 NZ_CP022881:1908503-1908688 [Staphylococcus sp. M0911]
ATGAGCTTGCATTTTACAATTCTTTTTTGGCTTTCACTTATATTTATCATAGCTGGCGCAATCATTCTAGCTATCATGCT
TAAAACTAAAAAAGAATCTAAGAAGGAATCTTATCTTGGTTTCACCATTGTATTCTTCATTTTTGGATTAGCAATGTTGA
TTTATACATTGTTATTCGGACTCTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9976.25 Da        Isoelectric Point: 4.6285

>AT79830 WP_002450867.1 NZ_CP022881:1908226-1908483 [Staphylococcus sp. M0911]
MKRYILHAINIILTILLIIFNVIITYNTNLDETLWLVPGLIVCGLIMMISFTIAITIKDLLSEVLFFINIILTLYYIYPI
FYDFL

Download         Length: 258 bp

>AT79830 NZ_CP022881:1908226-1908483 [Staphylococcus sp. M0911]
ATGAAACGATACATTTTACATGCAATCAATATCATTTTAACGATATTACTTATTATTTTTAATGTGATTATTACTTATAA
TACAAACCTAGACGAAACCTTATGGTTAGTGCCTGGATTAATTGTATGCGGTTTGATTATGATGATTAGCTTTACTATTG
CTATTACCATTAAGGACTTATTAAGTGAAGTTCTTTTCTTTATTAATATTATTCTTACACTGTATTACATTTATCCAATT
TTTTATGATTTTCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References