Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 990973..991779 Replicon chromosome
Accession NZ_CP022881
Organism Staphylococcus sp. M0911

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag ssp1_RS04945 Protein ID WP_049425065.1
Coordinates 991600..991779 (+) Length 60 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag ssp1_RS04940 Protein ID WP_002452098.1
Coordinates 990973..991572 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ssp1_RS04920 986758..988218 + 1461 WP_075779011.1 ABC transporter substrate-binding protein/permease -
ssp1_RS04925 988211..988933 + 723 WP_002452095.1 amino acid ABC transporter ATP-binding protein -
ssp1_RS04930 989191..990321 + 1131 WP_075779012.1 tRNA epoxyqueuosine(34) reductase QueG -
ssp1_RS04935 990322..990792 + 471 WP_002452097.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
ssp1_RS04940 990973..991572 + 600 WP_002452098.1 glucosamine-6-phosphate isomerase Antitoxin
ssp1_RS04945 991600..991779 + 180 WP_049425065.1 hypothetical protein Toxin
ssp1_RS04950 991933..992325 + 393 WP_002452100.1 hypothetical protein -
ssp1_RS04955 992480..993865 + 1386 WP_107533114.1 class II fumarate hydratase -
ssp1_RS04960 993924..994754 - 831 WP_118828141.1 RluA family pseudouridine synthase -
ssp1_RS04965 994932..996044 + 1113 WP_002452103.1 GAF domain-containing sensor histidine kinase -
ssp1_RS04970 996065..996688 + 624 WP_002452104.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(125-195)


Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6943.26 Da        Isoelectric Point: 3.8537

>T79829 WP_049425065.1 NZ_CP022881:991600-991779 [Staphylococcus sp. M0911]
MTQNKDSRTNYHEEENAMVTDLDDLKDLGKEMEQISEENDEDKLNQSHDSEVRSDLDQE

Download         Length: 180 bp

>T79829 NZ_CP022881:991600-991779 [Staphylococcus sp. M0911]
ATGACTCAAAATAAAGATTCTAGAACGAATTACCACGAAGAAGAAAATGCAATGGTAACTGATTTAGATGATTTAAAAGA
TTTAGGTAAAGAAATGGAACAAATTTCTGAAGAAAATGATGAAGATAAATTAAATCAATCTCATGATTCAGAAGTGCGTT
CTGATTTAGATCAAGAATAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22575.46 Da        Isoelectric Point: 4.8492

>AT79829 WP_002452098.1 NZ_CP022881:990973-991572 [Staphylococcus sp. M0911]
MAMNFKVFEDKQRVAEYTADILRKQFNNNPMTIAGVHLTKDHAPVLDELKKNVDLHAVDFSQINILDYDENQSYYEALGV
PQSQIYSLSYNQDANDFISDKIKTKENKGKLVLQVVSIDESGNLDVSVRQGLLEAREIFLVVTGSNKREVVEKLYNENGK
SNFEPADLKAHRMVNVILDKEAAAGLPEDVKEYFTARFA

Download         Length: 600 bp

>AT79829 NZ_CP022881:990973-991572 [Staphylococcus sp. M0911]
ATGGCAATGAACTTTAAAGTATTTGAAGATAAGCAAAGAGTAGCTGAATATACAGCGGATATTTTGAGAAAACAATTTAA
TAACAACCCAATGACTATCGCAGGTGTTCATTTAACAAAAGATCATGCACCTGTATTAGATGAATTAAAAAAGAATGTTG
ATTTACATGCAGTTGACTTCAGTCAAATTAACATTTTAGATTATGATGAAAATCAATCATATTATGAAGCGTTAGGTGTA
CCACAAAGTCAAATTTATTCATTATCATACAATCAAGATGCTAATGACTTTATTTCAGATAAAATTAAAACCAAAGAAAA
TAAAGGTAAATTAGTATTACAAGTGGTTTCAATTGATGAAAGCGGTAATTTAGACGTAAGTGTTAGACAAGGTTTATTAG
AAGCACGTGAAATCTTCTTAGTTGTTACTGGTAGTAATAAACGTGAAGTAGTTGAAAAATTATATAATGAAAATGGAAAA
TCTAATTTTGAACCAGCAGACTTAAAAGCGCACCGTATGGTTAACGTTATTTTAGATAAAGAAGCAGCAGCTGGATTACC
TGAAGACGTAAAAGAATACTTCACAGCTCGCTTTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References