Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2109236..2109376 Replicon chromosome
Accession NZ_CP022823
Organism Klebsiella quasivariicola strain KPN1705

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2109272..2109374 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2109236..2109376 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B8P98_RS10530 2104367..2106427 + 2061 WP_080896663.1 oligopeptidase B -
B8P98_RS10535 2106431..2107090 - 660 WP_080924781.1 exodeoxyribonuclease X -
B8P98_RS10540 2107169..2107399 - 231 WP_002911406.1 DNA polymerase III subunit theta -
B8P98_RS10545 2107513..2107887 + 375 WP_025711086.1 CopC domain-containing protein YobA -
B8P98_RS10550 2107889..2108758 + 870 WP_080924780.1 copper homeostasis membrane protein CopD -
B8P98_RS10555 2108775..2109113 + 339 WP_002911404.1 YebY family protein -
- 2109236..2109376 - 141 - - Antitoxin
- 2109272..2109374 + 103 - - Toxin
B8P98_RS10560 2109743..2110705 - 963 WP_025711084.1 glycosyltransferase -
B8P98_RS30445 2110980..2112116 - 1137 Protein_2008 IS3 family transposase -
B8P98_RS30450 2112338..2112481 - 144 WP_042929055.1 Ecr family regulatory small membrane protein -
B8P98_RS10570 2112585..2113553 - 969 WP_025711083.1 VirK/YbjX family protein -
B8P98_RS10575 2113711..2114364 + 654 WP_025711082.1 protein-serine/threonine phosphatase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2104319..2116393 12074


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T79806 NZ_CP022823:2109272-2109374 [Klebsiella quasivariicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT79806 NZ_CP022823:c2109376-2109236 [Klebsiella quasivariicola]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References