Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 63946..64556 Replicon plasmid unnamed
Accession NZ_CP022797
Organism Ralstonia solanacearum strain SL2312

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO97_RS16720 Protein ID WP_075465902.1
Coordinates 64248..64556 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO97_RS16715 Protein ID WP_013209163.1
Coordinates 63946..64251 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO97_RS16675 59108..59518 + 411 WP_075465861.1 acyl-CoA thioesterase -
CJO97_RS16680 59556..59948 + 393 WP_075465862.1 RidA family protein -
CJO97_RS16685 60264..60545 - 282 WP_075465894.1 hypothetical protein -
CJO97_RS16690 60678..60962 - 285 WP_075465896.1 hypothetical protein -
CJO97_RS16700 61296..61598 + 303 Protein_53 transposase -
CJO97_RS16705 61649..62317 + 669 WP_075465898.1 hypothetical protein -
CJO97_RS16710 62422..63735 - 1314 WP_118884159.1 metabolite/H+ symporter -
CJO97_RS16715 63946..64251 - 306 WP_013209163.1 putative addiction module antidote protein Antitoxin
CJO97_RS16720 64248..64556 - 309 WP_075465902.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO97_RS16725 64641..65840 - 1200 WP_118909475.1 MFS transporter -
CJO97_RS16730 65967..66782 - 816 WP_075465905.1 GntR family transcriptional regulator -
CJO97_RS16735 66956..67510 - 555 WP_118884160.1 helix-turn-helix transcriptional regulator -
CJO97_RS16740 67642..68238 + 597 WP_118884161.1 GNAT family N-acetyltransferase -
CJO97_RS16745 68494..68928 + 435 WP_013209169.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..1988567 1988567


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-85)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11795.54 Da        Isoelectric Point: 8.5237

>T79795 WP_075465902.1 NZ_CP022797:c64556-64248 [Ralstonia solanacearum]
MLTIRTTEIFDDWFCSLRDKAAQRRVQVRIDRLQMGNPGDVKAVREGIREMRIDHGPGYRVYFSQRGVVLIVLLCGGDKS
TQEADVRRAIDLSRRLDVDNME

Download         Length: 309 bp

>T79795 NZ_CP022797:c64556-64248 [Ralstonia solanacearum]
ATGCTGACAATCCGCACGACTGAAATCTTCGACGACTGGTTTTGCAGTCTCCGCGACAAGGCCGCGCAACGTCGCGTCCA
GGTGCGCATCGATCGCCTGCAGATGGGCAATCCAGGCGACGTGAAAGCTGTACGTGAAGGCATCCGTGAGATGCGGATCG
ATCATGGCCCGGGCTATCGCGTGTATTTTTCACAGCGTGGCGTGGTCCTGATCGTCCTGCTGTGCGGCGGTGACAAGTCG
ACGCAGGAAGCCGATGTCCGCCGCGCAATCGACCTGTCCCGCCGTCTTGACGTGGACAACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11009.67 Da        Isoelectric Point: 6.7174

>AT79795 WP_013209163.1 NZ_CP022797:c64251-63946 [Ralstonia solanacearum]
MMMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARARGMTQIARETGMTREGLYKALSEDGNP
SFATVLKVIRALGIRLHAVPA

Download         Length: 306 bp

>AT79795 NZ_CP022797:c64251-63946 [Ralstonia solanacearum]
ATGATGATGGCCCAACGCACCATAAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTATCTCGACGCCTGCCTGGAGGAAGCCGGGGATGACCCCGCATTCATCACGCACGCGCTGGGCGTGGTCGCGCGGGCGC
GCGGCATGACGCAGATCGCCCGCGAGACCGGGATGACGCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGACGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References