Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 49835..50364 Replicon plasmid unnamed
Accession NZ_CP022795
Organism Ralstonia solanacearum strain SL2330

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO96_RS17275 Protein ID WP_011003396.1
Coordinates 50137..50364 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO96_RS17270 Protein ID WP_019719757.1
Coordinates 49835..50140 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO96_RS17240 45335..45820 + 486 WP_016726511.1 hypothetical protein -
CJO96_RS17245 46151..46432 - 282 WP_019719760.1 hypothetical protein -
CJO96_RS17250 46565..46849 - 285 WP_111375044.1 hypothetical protein -
CJO96_RS17255 47182..47369 + 188 Protein_44 IS5/IS1182 family transposase -
CJO96_RS17260 47536..48204 + 669 WP_038938024.1 hypothetical protein -
CJO96_RS17265 48309..49622 - 1314 WP_064478230.1 metabolite/H+ symporter -
CJO96_RS17270 49835..50140 - 306 WP_019719757.1 putative addiction module antidote protein Antitoxin
CJO96_RS17275 50137..50364 - 228 WP_011003396.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO96_RS17280 50520..51719 - 1200 WP_118872522.1 MFS transporter -
CJO96_RS17285 51846..52667 - 822 WP_011003398.1 GntR family transcriptional regulator -
CJO96_RS17290 52845..53396 - 552 WP_011003399.1 helix-turn-helix transcriptional regulator -
CJO96_RS17295 53529..54128 + 600 WP_071013505.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / htpB / adeG / cheY / cheB / cheW / motA 1..2001855 2001855


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-62)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8544.80 Da        Isoelectric Point: 6.4584

>T79792 WP_011003396.1 NZ_CP022795:c50364-50137 [Ralstonia solanacearum]
VRIDRLQMGNPGDMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T79792 NZ_CP022795:c50364-50137 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCAACCCGGGCGACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10982.63 Da        Isoelectric Point: 8.0666

>AT79792 WP_019719757.1 NZ_CP022795:c50140-49835 [Ralstonia solanacearum]
MTMAQRTIKTRLWDSAEHLRTEADIAAYLDACLEEAGDNPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT79792 NZ_CP022795:c50140-49835 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCTGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATAACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References