Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 1957981..1958510 Replicon plasmid unnamed
Accession NZ_CP022791
Organism Ralstonia solanacearum strain SL3103

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO93_RS24295 Protein ID WP_016722340.1
Coordinates 1957981..1958208 (+) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO93_RS24300 Protein ID WP_016722339.1
Coordinates 1958205..1958510 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO93_RS24275 1954218..1954817 - 600 WP_016722344.1 GNAT family N-acetyltransferase -
CJO93_RS24280 1954950..1955501 + 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
CJO93_RS24285 1955679..1956500 + 822 WP_011003398.1 GntR family transcriptional regulator -
CJO93_RS24290 1956627..1957826 + 1200 WP_016726513.1 MFS transporter -
CJO93_RS24295 1957981..1958208 + 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO93_RS24300 1958205..1958510 + 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
CJO93_RS24305 1958723..1960036 + 1314 WP_038938025.1 metabolite/H+ symporter -
CJO93_RS24310 1960141..1960808 - 668 Protein_1527 hypothetical protein -
CJO93_RS24315 1960975..1961192 - 218 Protein_1528 transposase -
CJO93_RS24320 1961413..1962219 - 807 Protein_1529 IS5-like element IS1420 family transposase -
CJO93_RS24325 1962370..1963326 + 957 WP_069078857.1 IS5-like element IS1420 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..2134747 2134747


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T79785 WP_016722340.1 NZ_CP022791:1957981-1958208 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T79785 NZ_CP022791:1957981-1958208 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT79785 WP_016722339.1 NZ_CP022791:1958205-1958510 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT79785 NZ_CP022791:1958205-1958510 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References