Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 64478..65088 Replicon plasmid unnamed
Accession NZ_CP022789
Organism Ralstonia solanacearum strain SL3175

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO92_RS16970 Protein ID WP_118870132.1
Coordinates 64780..65088 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO92_RS16965 Protein ID WP_013209163.1
Coordinates 64478..64783 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO92_RS16930 60444..60854 + 411 WP_013209158.1 acyl-CoA thioesterase -
CJO92_RS16935 60892..61284 + 393 WP_013209159.1 RidA family protein -
CJO92_RS16940 61600..61881 - 282 WP_013209160.1 hypothetical protein -
CJO92_RS16945 62014..62298 - 285 WP_078223782.1 hypothetical protein -
CJO92_RS16955 62633..62749 + 117 Protein_55 IS5/IS1182 family transposase -
CJO92_RS16960 62954..64267 - 1314 WP_013209162.1 metabolite/H+ symporter -
CJO92_RS16965 64478..64783 - 306 WP_013209163.1 putative addiction module antidote protein Antitoxin
CJO92_RS16970 64780..65088 - 309 WP_118870132.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO92_RS16975 65173..66372 - 1200 WP_118870133.1 MFS transporter -
CJO92_RS16980 66500..67315 - 816 WP_013209166.1 GntR family transcriptional regulator -
CJO92_RS16985 67489..68040 - 552 WP_048816929.1 helix-turn-helix transcriptional regulator -
CJO92_RS16990 68172..68768 + 597 WP_013209168.1 GNAT family N-acetyltransferase -
CJO92_RS16995 69031..69465 + 435 WP_013209169.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / flgC / flgG / fliM / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..1986284 1986284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11731.50 Da        Isoelectric Point: 8.5237

>T79781 WP_118870132.1 NZ_CP022789:c65088-64780 [Ralstonia solanacearum]
MLTIRTTEIFDDWFCSLRDKAAQRRVQVRIDRLQMGNPGDVKAVREGIREMRIDHGPGYRVYVAQRGVVLIVLLCGGDKS
TQEADVRRAIDLSRRLDVDNME

Download         Length: 309 bp

>T79781 NZ_CP022789:c65088-64780 [Ralstonia solanacearum]
ATGCTGACAATCCGCACGACTGAAATCTTCGACGACTGGTTTTGCAGTCTCCGCGACAAGGCCGCGCAACGCCGCGTCCA
GGTGCGCATCGATCGCCTGCAGATGGGCAATCCAGGCGATGTGAAAGCTGTACGTGAAGGCATCCGTGAGATGCGGATCG
ATCATGGCCCGGGCTATCGCGTGTATGTTGCACAGCGTGGCGTGGTCCTGATCGTCCTGCTGTGCGGCGGTGACAAGTCG
ACGCAGGAAGCCGATGTCCGCCGCGCAATCGACCTGTCCCGCCGTCTTGACGTGGACAACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11009.67 Da        Isoelectric Point: 6.7174

>AT79781 WP_013209163.1 NZ_CP022789:c64783-64478 [Ralstonia solanacearum]
MMMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARARGMTQIARETGMTREGLYKALSEDGNP
SFATVLKVIRALGIRLHAVPA

Download         Length: 306 bp

>AT79781 NZ_CP022789:c64783-64478 [Ralstonia solanacearum]
ATGATGATGGCCCAACGCACCATAAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTATCTCGACGCCTGCCTGGAGGAAGCCGGGGATGACCCCGCATTCATCACGCACGCGCTGGGCGTGGTCGCGCGGGCGC
GCGGCATGACGCAGATCGCCCGCGAGACCGGGATGACGCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGACGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References