Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2208721..2209261 Replicon chromosome
Accession NZ_CP022788
Organism Ralstonia solanacearum strain SL3175

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CJO92_RS10125 Protein ID WP_048817440.1
Coordinates 2208721..2208981 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO92_RS10130 Protein ID WP_118869591.1
Coordinates 2208974..2209261 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO92_RS10105 2204853..2205770 - 918 WP_013212788.1 sugar ABC transporter substrate-binding protein -
CJO92_RS10110 2205981..2207033 - 1053 WP_013212789.1 LacI family DNA-binding transcriptional regulator -
CJO92_RS10115 2207169..2208317 + 1149 WP_118869590.1 fatty acid desaturase family protein -
CJO92_RS10120 2208283..2208594 + 312 WP_048817439.1 Rieske 2Fe-2S domain-containing protein -
CJO92_RS10125 2208721..2208981 + 261 WP_048817440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO92_RS10130 2208974..2209261 + 288 WP_118869591.1 putative addiction module antidote protein Antitoxin
CJO92_RS10135 2209274..2210119 - 846 WP_013212795.1 TIM barrel protein -
CJO92_RS10140 2210116..2211153 - 1038 WP_013212796.1 hypothetical protein -
CJO92_RS10145 2211150..2212439 - 1290 WP_118869592.1 FAD-dependent oxidoreductase -
CJO92_RS10150 2212606..2213523 + 918 WP_118869593.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(8-93)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9435.79 Da        Isoelectric Point: 10.3136

>T79780 WP_048817440.1 NZ_CP022788:2208721-2208981 [Ralstonia solanacearum]
MRDKRAKARIAARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGNKATQAQDIKQAIRMARDL
KESGHD

Download         Length: 261 bp

>T79780 NZ_CP022788:2208721-2208981 [Ralstonia solanacearum]
CTGCGCGACAAGCGTGCCAAGGCGCGGATCGCCGCCCGGCTGGTCAGCGCATCGTTCGGGAATTTCGGCGACTGCAAGCC
GGTGGGTGAAGGCGTGAGCGAGATGCGGATCGATGTGGGCGCCGGGTATCGCGTCTACTACACGCGACAAGGTACTGTCG
TCTACATCCTGCTCACGGGCGGCAACAAGGCAACCCAAGCCCAGGACATCAAGCAAGCCATCCGGATGGCACGCGACCTG
AAGGAGTCAGGCCATGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10003.40 Da        Isoelectric Point: 4.7318

>AT79780 WP_118869591.1 NZ_CP022788:2208974-2209261 [Ralstonia solanacearum]
MTETYAPFDAAAYLDSEETIAEFLAAAMEDPNPDVFLAALGAVARAHGIAKVAADAGLGRESLYKAISPGAHPRYETIQK
IMRALGVRLNVTPAA

Download         Length: 288 bp

>AT79780 NZ_CP022788:2208974-2209261 [Ralstonia solanacearum]
ATGACTGAAACCTACGCACCGTTTGACGCGGCGGCCTACCTCGATAGCGAAGAGACCATCGCCGAATTTCTGGCGGCCGC
GATGGAAGACCCGAATCCGGATGTCTTCCTGGCTGCCCTCGGTGCCGTTGCGCGCGCCCACGGCATTGCCAAGGTGGCTG
CGGACGCGGGCCTGGGGCGCGAAAGCCTGTACAAGGCCATCAGCCCCGGCGCGCACCCGCGCTACGAAACCATCCAGAAA
ATCATGCGCGCACTGGGCGTCAGGCTGAACGTGACGCCTGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References