Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 52188..52717 Replicon plasmid unnamed
Accession NZ_CP022787
Organism Ralstonia solanacearum strain SL3300

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO91_RS18510 Protein ID WP_016722340.1
Coordinates 52490..52717 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO91_RS18505 Protein ID WP_016722339.1
Coordinates 52188..52493 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO91_RS18475 47326..47607 - 282 WP_016722336.1 hypothetical protein -
CJO91_RS18480 47738..48022 - 285 WP_011003391.1 hypothetical protein -
CJO91_RS18485 48453..49418 + 966 WP_016721735.1 IS5 family transposase -
CJO91_RS26770 49415..49564 + 150 WP_155738951.1 hypothetical protein -
CJO91_RS18490 49571..49722 + 152 Protein_48 IS5/IS1182 family transposase -
CJO91_RS18495 49889..50557 + 669 WP_038938024.1 hypothetical protein -
CJO91_RS18500 50662..51975 - 1314 WP_038938025.1 metabolite/H+ symporter -
CJO91_RS18505 52188..52493 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
CJO91_RS18510 52490..52717 - 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO91_RS18515 52872..54071 - 1200 WP_016726513.1 MFS transporter -
CJO91_RS18520 54198..55019 - 822 WP_011003398.1 GntR family transcriptional regulator -
CJO91_RS18525 55197..55748 - 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
CJO91_RS18530 55881..56480 + 600 WP_118888101.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..2033766 2033766
- flank IS/Tn - - 48453..49418 965


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T79778 WP_016722340.1 NZ_CP022787:c52717-52490 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T79778 NZ_CP022787:c52717-52490 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT79778 WP_016722339.1 NZ_CP022787:c52493-52188 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT79778 NZ_CP022787:c52493-52188 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References