Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 49830..50359 Replicon plasmid unnamed
Accession NZ_CP022783
Organism Ralstonia solanacearum strain SL3755

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO89_RS17910 Protein ID WP_011003396.1
Coordinates 50132..50359 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO89_RS17905 Protein ID WP_019719757.1
Coordinates 49830..50135 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO89_RS17875 45330..45815 + 486 WP_016726511.1 hypothetical protein -
CJO89_RS17880 46146..46427 - 282 WP_019719760.1 hypothetical protein -
CJO89_RS17885 46560..46844 - 285 WP_111375044.1 hypothetical protein -
CJO89_RS17890 47177..47364 + 188 Protein_44 IS5/IS1182 family transposase -
CJO89_RS17895 47531..48199 + 669 WP_038938024.1 hypothetical protein -
CJO89_RS17900 48304..49617 - 1314 WP_064478230.1 metabolite/H+ symporter -
CJO89_RS17905 49830..50135 - 306 WP_019719757.1 putative addiction module antidote protein Antitoxin
CJO89_RS17910 50132..50359 - 228 WP_011003396.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO89_RS17915 50515..51714 - 1200 WP_118872522.1 MFS transporter -
CJO89_RS17920 51841..52662 - 822 WP_011003398.1 GntR family transcriptional regulator -
CJO89_RS17925 52840..53391 - 552 WP_011003399.1 helix-turn-helix transcriptional regulator -
CJO89_RS17930 53524..54123 + 600 WP_071013505.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / htpB / adeG / cheY / cheB / cheW / motA 1..2006167 2006167


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-62)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8544.80 Da        Isoelectric Point: 6.4584

>T79770 WP_011003396.1 NZ_CP022783:c50359-50132 [Ralstonia solanacearum]
VRIDRLQMGNPGDMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T79770 NZ_CP022783:c50359-50132 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCAACCCGGGCGACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10982.63 Da        Isoelectric Point: 8.0666

>AT79770 WP_019719757.1 NZ_CP022783:c50135-49830 [Ralstonia solanacearum]
MTMAQRTIKTRLWDSAEHLRTEADIAAYLDACLEEAGDNPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT79770 NZ_CP022783:c50135-49830 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCTGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATAACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References