Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 51010..51539 Replicon plasmid unnamed
Accession NZ_CP022781
Organism Ralstonia solanacearum strain SL3822

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO88_RS18015 Protein ID WP_016722340.1
Coordinates 51312..51539 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO88_RS18010 Protein ID WP_016722339.1
Coordinates 51010..51315 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO88_RS17980 46148..46429 - 282 WP_016722336.1 hypothetical protein -
CJO88_RS17985 46560..46844 - 285 WP_011003391.1 hypothetical protein -
CJO88_RS17990 47275..48240 + 966 WP_016721735.1 IS5 family transposase -
CJO88_RS26675 48237..48386 + 150 WP_155738951.1 hypothetical protein -
CJO88_RS17995 48393..48544 + 152 Protein_46 IS5/IS1182 family transposase -
CJO88_RS18000 48711..49379 + 669 WP_038938024.1 hypothetical protein -
CJO88_RS18005 49484..50797 - 1314 WP_038938025.1 metabolite/H+ symporter -
CJO88_RS18010 51010..51315 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
CJO88_RS18015 51312..51539 - 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO88_RS18020 51694..52893 - 1200 WP_016726513.1 MFS transporter -
CJO88_RS18025 53020..53841 - 822 WP_011003398.1 GntR family transcriptional regulator -
CJO88_RS18030 54019..54570 - 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
CJO88_RS18035 54703..55302 + 600 WP_118888101.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - motA / cheW / cheB / cheY / adeG / acrB / fliI / fliG / fliM / flgG / flgC / cyaB 1..2134808 2134808
- flank IS/Tn - - 47275..48240 965


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T79765 WP_016722340.1 NZ_CP022781:c51539-51312 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T79765 NZ_CP022781:c51539-51312 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT79765 WP_016722339.1 NZ_CP022781:c51315-51010 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT79765 NZ_CP022781:c51315-51010 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References