Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 91630..92240 Replicon plasmid unnamed
Accession NZ_CP022777
Organism Ralstonia solanacearum strain T11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO86_RS17160 Protein ID WP_075465902.1
Coordinates 91932..92240 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO86_RS17155 Protein ID WP_118868926.1
Coordinates 91630..91935 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO86_RS17125 87960..88241 - 282 WP_075465894.1 hypothetical protein -
CJO86_RS17130 88374..88658 - 285 WP_075465896.1 hypothetical protein -
CJO86_RS17140 88992..89294 + 303 Protein_71 transposase -
CJO86_RS17145 89345..90013 + 669 WP_075465898.1 hypothetical protein -
CJO86_RS17150 90118..91419 - 1302 WP_118868925.1 MFS transporter -
CJO86_RS17155 91630..91935 - 306 WP_118868926.1 putative addiction module antidote protein Antitoxin
CJO86_RS17160 91932..92240 - 309 WP_075465902.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO86_RS17165 92325..93524 - 1200 WP_075465903.1 MFS transporter -
CJO86_RS17170 93652..94467 - 816 WP_075465905.1 GntR family transcriptional regulator -
CJO86_RS17175 94641..95195 - 555 WP_075465907.1 helix-turn-helix transcriptional regulator -
CJO86_RS17180 95327..95923 + 597 WP_075465909.1 GNAT family N-acetyltransferase -
CJO86_RS17185 96179..96613 + 435 WP_013209169.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..1883805 1883805


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-85)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11795.54 Da        Isoelectric Point: 8.5237

>T79756 WP_075465902.1 NZ_CP022777:c92240-91932 [Ralstonia solanacearum]
MLTIRTTEIFDDWFCSLRDKAAQRRVQVRIDRLQMGNPGDVKAVREGIREMRIDHGPGYRVYFSQRGVVLIVLLCGGDKS
TQEADVRRAIDLSRRLDVDNME

Download         Length: 309 bp

>T79756 NZ_CP022777:c92240-91932 [Ralstonia solanacearum]
ATGCTGACAATCCGCACGACTGAAATCTTCGACGACTGGTTTTGCAGTCTCCGCGACAAGGCCGCGCAACGTCGCGTCCA
GGTGCGCATCGATCGCCTGCAGATGGGCAATCCAGGCGACGTGAAAGCTGTACGTGAAGGCATCCGTGAGATGCGGATCG
ATCATGGCCCGGGCTATCGCGTGTATTTTTCACAGCGTGGCGTGGTCCTGATCGTCCTGCTGTGCGGCGGTGACAAGTCG
ACGCAGGAAGCCGATGTCCGCCGCGCAATCGACCTGTCCCGCCGTCTTGACGTGGACAACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11000.66 Da        Isoelectric Point: 6.4607

>AT79756 WP_118868926.1 NZ_CP022777:c91935-91630 [Ralstonia solanacearum]
MMMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITQALGVVARARGMTQIARETGMTREGLYKALSEDGNP
SFATVLKVIRALGIRLHAVPA

Download         Length: 306 bp

>AT79756 NZ_CP022777:c91935-91630 [Ralstonia solanacearum]
ATGATGATGGCCCAACGCACCATAAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTATCTCGACGCCTGCCTGGAGGAAGCCGGGGATGACCCCGCATTCATCACGCAGGCGCTGGGCGTGGTCGCGCGTGCGC
GCGGCATGACGCAGATCGCCCGCGAGACCGGGATGACGCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGACGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References