Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2252829..2253369 Replicon chromosome
Accession NZ_CP022776
Organism Ralstonia solanacearum strain T11

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CJO86_RS10555 Protein ID WP_048817440.1
Coordinates 2252829..2253089 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO86_RS10560 Protein ID WP_075464691.1
Coordinates 2253082..2253369 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO86_RS10535 2248946..2249863 - 918 WP_075464683.1 sugar ABC transporter substrate-binding protein -
CJO86_RS10540 2250081..2251133 - 1053 WP_075464685.1 LacI family DNA-binding transcriptional regulator -
CJO86_RS10545 2251268..2252425 + 1158 WP_075464687.1 fatty acid desaturase family protein -
CJO86_RS10550 2252391..2252702 + 312 WP_075464689.1 Rieske 2Fe-2S domain-containing protein -
CJO86_RS10555 2252829..2253089 + 261 WP_048817440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO86_RS10560 2253082..2253369 + 288 WP_075464691.1 putative addiction module antidote protein Antitoxin
CJO86_RS10565 2253382..2254227 - 846 WP_075464693.1 TIM barrel protein -
CJO86_RS10570 2254224..2255261 - 1038 WP_075464695.1 xylose isomerase -
CJO86_RS10575 2255258..2256547 - 1290 WP_075464697.1 FAD-dependent oxidoreductase -
CJO86_RS10580 2256714..2257631 + 918 WP_075464699.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(8-93)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9435.79 Da        Isoelectric Point: 10.3136

>T79755 WP_048817440.1 NZ_CP022776:2252829-2253089 [Ralstonia solanacearum]
MRDKRAKARIAARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGNKATQAQDIKQAIRMARDL
KESGHD

Download         Length: 261 bp

>T79755 NZ_CP022776:2252829-2253089 [Ralstonia solanacearum]
CTGCGCGACAAGCGTGCCAAGGCGCGGATCGCCGCCCGGCTGGTCAGCGCGTCGTTCGGGAATTTCGGCGACTGCAAGCC
GGTGGGTGAAGGCGTGAGCGAGATGCGGATCGATGTGGGCGCCGGGTATCGCGTCTACTACACGCGACAAGGTACTGTCG
TCTACATCCTGCTCACGGGCGGCAACAAGGCAACCCAAGCCCAGGACATCAAGCAAGCCATCCGGATGGCGCGCGACCTG
AAGGAGTCAGGCCATGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10052.47 Da        Isoelectric Point: 4.7361

>AT79755 WP_075464691.1 NZ_CP022776:2253082-2253369 [Ralstonia solanacearum]
MTETYAPFDAAAYLDSEETIAEFLAAAMEDPNPDVFLAALGAVARARGITKVAADAGLGRESLYKAISPGAHPRYETIQK
IMRALGVRLNVTPAA

Download         Length: 288 bp

>AT79755 NZ_CP022776:2253082-2253369 [Ralstonia solanacearum]
ATGACTGAGACCTACGCACCGTTTGACGCGGCGGCCTACCTCGATAGCGAAGAGACCATCGCCGAATTTCTGGCGGCCGC
AATGGAAGACCCGAATCCGGATGTCTTCCTGGCTGCCCTCGGTGCCGTTGCGCGCGCCCGCGGCATTACCAAGGTGGCTG
CGGACGCGGGCCTGGGGCGCGAAAGCCTGTACAAGGCCATCAGCCCCGGCGCGCACCCGCGCTACGAAACCATCCAGAAA
ATCATGCGCGCATTGGGCGTCAGGCTGAACGTGACGCCTGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References