Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2214933..2215473 Replicon chromosome
Accession NZ_CP022774
Organism Ralstonia solanacearum strain T12

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CJO85_RS10300 Protein ID WP_048817440.1
Coordinates 2214933..2215193 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO85_RS10305 Protein ID WP_013212794.1
Coordinates 2215186..2215473 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO85_RS10280 (CJO85_10175) 2211066..2211983 - 918 WP_075464683.1 sugar ABC transporter substrate-binding protein -
CJO85_RS10285 (CJO85_10180) 2212194..2213246 - 1053 WP_118883343.1 LacI family DNA-binding transcriptional regulator -
CJO85_RS10290 (CJO85_10185) 2213381..2214529 + 1149 WP_118883344.1 fatty acid desaturase family protein -
CJO85_RS10295 (CJO85_10190) 2214495..2214806 + 312 WP_075464689.1 Rieske 2Fe-2S domain-containing protein -
CJO85_RS10300 (CJO85_10195) 2214933..2215193 + 261 WP_048817440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO85_RS10305 (CJO85_10200) 2215186..2215473 + 288 WP_013212794.1 putative addiction module antidote protein Antitoxin
CJO85_RS10310 (CJO85_10205) 2215486..2216331 - 846 WP_013212795.1 TIM barrel protein -
CJO85_RS10315 (CJO85_10210) 2216328..2217365 - 1038 WP_118883345.1 xylose isomerase -
CJO85_RS10320 (CJO85_10215) 2217362..2218651 - 1290 WP_118883346.1 FAD-dependent oxidoreductase -
CJO85_RS10325 (CJO85_10220) 2218818..2219735 + 918 WP_075464699.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9435.79 Da        Isoelectric Point: 10.3136

>T79752 WP_048817440.1 NZ_CP022774:2214933-2215193 [Ralstonia solanacearum]
MRDKRAKARIAARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGNKATQAQDIKQAIRMARDL
KESGHD

Download         Length: 261 bp

>T79752 NZ_CP022774:2214933-2215193 [Ralstonia solanacearum]
CTGCGCGACAAGCGTGCCAAGGCGCGGATCGCCGCCCGGCTGGTCAGCGCGTCGTTCGGAAATTTCGGCGACTGCAAGCC
GGTGGGTGAAGGCGTGAGCGAGATGCGGATCGATGTGGGCGCCGGGTATCGCGTCTACTACACGCGACAAGGTACTGTCG
TCTACATCCTGCTCACGGGCGGCAACAAGGCAACCCAAGCCCAGGACATCAAGCAAGCCATCCGGATGGCGCGCGACCTG
AAGGAGTCAGGCCATGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10022.45 Da        Isoelectric Point: 4.7361

>AT79752 WP_013212794.1 NZ_CP022774:2215186-2215473 [Ralstonia solanacearum]
MTETYAPFDAAAYLDSEETIAEFLAAAMEDPNPDVFLAALGAVARARGIAKVAADAGLGRESLYKAISPGAHPRYETIQK
IMRALGVRLNVTPAA

Download         Length: 288 bp

>AT79752 NZ_CP022774:2215186-2215473 [Ralstonia solanacearum]
ATGACTGAGACCTACGCACCGTTTGACGCGGCGGCCTACCTCGATAGCGAAGAGACCATCGCCGAATTTCTGGCGGCCGC
AATGGAAGACCCGAATCCGGATGTCTTCCTGGCTGCCCTCGGTGCCGTTGCGCGCGCCCGCGGCATTGCCAAGGTGGCTG
CGGACGCGGGCCTGGGGCGCGAAAGCCTGTACAAGGCCATCAGCCCCGGCGCGCACCCGCGCTACGAAACCATCCAGAAA
ATCATGCGCGCATTGGGCGTCAGGCTGAACGTGACGCCTGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References