Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 51013..51542 Replicon plasmid unnamed
Accession NZ_CP022766
Organism Ralstonia solanacearum strain T78

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO80_RS18980 Protein ID WP_016722340.1
Coordinates 51315..51542 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO80_RS18975 Protein ID WP_016722339.1
Coordinates 51013..51318 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO80_RS18945 46151..46432 - 282 WP_016722336.1 hypothetical protein -
CJO80_RS18950 46563..46847 - 285 WP_011003391.1 hypothetical protein -
CJO80_RS18955 47278..48243 + 966 WP_016721735.1 IS5 family transposase -
CJO80_RS28050 48240..48389 + 150 WP_155738951.1 hypothetical protein -
CJO80_RS18960 48396..48547 + 152 Protein_46 IS5/IS1182 family transposase -
CJO80_RS18965 48714..49382 + 669 WP_038938024.1 hypothetical protein -
CJO80_RS18970 49487..50800 - 1314 WP_038938025.1 metabolite/H+ symporter -
CJO80_RS18975 51013..51318 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
CJO80_RS18980 51315..51542 - 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO80_RS18985 51697..52896 - 1200 WP_118891228.1 MFS transporter -
CJO80_RS18990 53022..53843 - 822 WP_011003398.1 GntR family transcriptional regulator -
CJO80_RS18995 54021..54572 - 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
CJO80_RS19000 54704..55302 + 599 Protein_54 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..2063152 2063152
- flank IS/Tn - - 47278..48243 965


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T79738 WP_016722340.1 NZ_CP022766:c51542-51315 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T79738 NZ_CP022766:c51542-51315 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT79738 WP_016722339.1 NZ_CP022766:c51318-51013 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT79738 NZ_CP022766:c51318-51013 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References