Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 245074..245735 Replicon chromosome
Accession NZ_CP022765
Organism Ralstonia solanacearum strain T78

Toxin (Protein)


Gene name vapC Uniprot ID A0A9E7Z845
Locus tag CJO80_RS01205 Protein ID WP_016727753.1
Coordinates 245074..245487 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A9E7Z6P3
Locus tag CJO80_RS01210 Protein ID WP_019717749.1
Coordinates 245484..245735 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO80_RS01165 240163..240465 + 303 WP_021154690.1 hypothetical protein -
CJO80_RS01170 240471..240917 + 447 WP_016723649.1 hypothetical protein -
CJO80_RS01175 241018..241791 + 774 WP_023470086.1 hypothetical protein -
CJO80_RS01180 241800..242189 + 390 WP_043897859.1 hypothetical protein -
CJO80_RS01185 242186..242407 + 222 WP_020833043.1 hypothetical protein -
CJO80_RS01190 242382..243026 + 645 WP_118891071.1 hypothetical protein -
CJO80_RS01195 243069..243356 - 288 WP_019717747.1 H-NS histone family protein -
CJO80_RS01200 243980..245002 + 1023 WP_081326687.1 DNA cytosine methyltransferase -
CJO80_RS01205 245074..245487 - 414 WP_016727753.1 type II toxin-antitoxin system VapC family toxin Toxin
CJO80_RS01210 245484..245735 - 252 WP_019717749.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CJO80_RS01215 246112..246345 + 234 WP_081326699.1 hypothetical protein -
CJO80_RS01220 246394..246525 + 132 Protein_237 IS5/IS1182 family transposase -
CJO80_RS27605 246694..247908 - 1215 WP_162905114.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 217361..257655 40294
- flank IS/Tn - - 246412..246525 113


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15586.89 Da        Isoelectric Point: 6.2337

>T79735 WP_016727753.1 NZ_CP022765:c245487-245074 [Ralstonia solanacearum]
MSYLIDTNVLSELRRKAPDARVVAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLEVELPNYFLGRLLDID
AHTADRWGRLMSSAGRPLPAIDGLLAATALQHDLTLVTRNTKDFAGLDVQLINPWEA

Download         Length: 414 bp

>T79735 NZ_CP022765:c245487-245074 [Ralstonia solanacearum]
TTGAGTTACCTGATCGACACCAATGTCCTGTCCGAATTGCGCCGCAAAGCGCCCGATGCGCGCGTGGTGGCCTGGATGCA
GGACCGCCCGCGCCAGTCGCTCTACCTGAGCGTGCTGACCCTGGGCGAGATTCGCAAAGGTATCGAGCGGCTGGACGACG
CGGCGCGCCGCCAGCACCTGATTGACTGGCTCGAAGTGGAACTGCCGAACTACTTTCTCGGCCGATTGCTCGACATCGAT
GCGCATACCGCCGACCGCTGGGGCCGGCTGATGTCCTCGGCCGGCCGCCCCCTGCCCGCCATCGACGGCCTGCTGGCCGC
GACCGCCCTGCAACACGACCTCACGCTGGTCACGCGCAACACCAAGGATTTCGCGGGGCTCGACGTCCAGCTCATCAACC
CATGGGAAGCCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9305.49 Da        Isoelectric Point: 5.0774

>AT79735 WP_019717749.1 NZ_CP022765:c245735-245484 [Ralstonia solanacearum]
MQSWQMQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGGGESLVSFMRQSPLADQDDVVFERERSLPRE
VEF

Download         Length: 252 bp

>AT79735 NZ_CP022765:c245735-245484 [Ralstonia solanacearum]
ATGCAAAGCTGGCAAATGCAGGCCGCCAAGGCGCGGTTTTCCGATGTCGTGAAGCGGGCGGCAGACGATGGCCCGCAGGA
AATCACCGTGCATGGCCGCCCGGTGGCGGTGGTGATCTCGCGCGCACTGTTCGATCGCTTGAGCGGCGGCGGTGAGTCGC
TGGTCAGCTTCATGCGCCAATCCCCGCTGGCCGACCAGGACGATGTCGTCTTTGAGCGCGAGCGCAGCCTGCCGCGCGAG
GTCGAGTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References