Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2208705..2209245 Replicon chromosome
Accession NZ_CP022759
Organism Ralstonia solanacearum strain T98

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CJO77_RS10130 Protein ID WP_048817440.1
Coordinates 2208705..2208965 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO77_RS10135 Protein ID WP_118869591.1
Coordinates 2208958..2209245 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO77_RS10110 2204837..2205754 - 918 WP_013212788.1 sugar ABC transporter substrate-binding protein -
CJO77_RS10115 2205965..2207017 - 1053 WP_013212789.1 LacI family DNA-binding transcriptional regulator -
CJO77_RS10120 2207153..2208301 + 1149 WP_118869590.1 fatty acid desaturase family protein -
CJO77_RS10125 2208267..2208578 + 312 WP_048817439.1 Rieske 2Fe-2S domain-containing protein -
CJO77_RS10130 2208705..2208965 + 261 WP_048817440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO77_RS10135 2208958..2209245 + 288 WP_118869591.1 putative addiction module antidote protein Antitoxin
CJO77_RS10140 2209258..2210103 - 846 WP_013212795.1 TIM barrel protein -
CJO77_RS10145 2210100..2211137 - 1038 WP_013212796.1 hypothetical protein -
CJO77_RS10150 2211134..2212423 - 1290 WP_118869592.1 FAD-dependent oxidoreductase -
CJO77_RS10155 2212590..2213507 + 918 WP_118869593.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(8-93)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9435.79 Da        Isoelectric Point: 10.3136

>T79724 WP_048817440.1 NZ_CP022759:2208705-2208965 [Ralstonia solanacearum]
MRDKRAKARIAARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGNKATQAQDIKQAIRMARDL
KESGHD

Download         Length: 261 bp

>T79724 NZ_CP022759:2208705-2208965 [Ralstonia solanacearum]
CTGCGCGACAAGCGTGCCAAGGCGCGGATCGCCGCCCGGCTGGTCAGCGCATCGTTCGGGAATTTCGGCGACTGCAAGCC
GGTGGGTGAAGGCGTGAGCGAGATGCGGATCGATGTGGGCGCCGGGTATCGCGTCTACTACACGCGACAAGGTACTGTCG
TCTACATCCTGCTCACGGGCGGCAACAAGGCAACCCAAGCCCAGGACATCAAGCAAGCCATCCGGATGGCACGCGACCTG
AAGGAGTCAGGCCATGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10003.40 Da        Isoelectric Point: 4.7318

>AT79724 WP_118869591.1 NZ_CP022759:2208958-2209245 [Ralstonia solanacearum]
MTETYAPFDAAAYLDSEETIAEFLAAAMEDPNPDVFLAALGAVARAHGIAKVAADAGLGRESLYKAISPGAHPRYETIQK
IMRALGVRLNVTPAA

Download         Length: 288 bp

>AT79724 NZ_CP022759:2208958-2209245 [Ralstonia solanacearum]
ATGACTGAAACCTACGCACCGTTTGACGCGGCGGCCTACCTCGATAGCGAAGAGACCATCGCCGAATTTCTGGCGGCCGC
GATGGAAGACCCGAATCCGGATGTCTTCCTGGCTGCCCTCGGTGCCGTTGCGCGCGCCCACGGCATTGCCAAGGTGGCTG
CGGACGCGGGCCTGGGGCGCGAAAGCCTGTACAAGGCCATCAGCCCCGGCGCGCACCCGCGCTACGAAACCATCCAGAAA
ATCATGCGCGCACTGGGCGTCAGGCTGAACGTGACGCCTGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References