Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 63945..64555 Replicon plasmid unnamed
Accession NZ_CP022758
Organism Ralstonia solanacearum strain T101

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO76_RS16730 Protein ID WP_075465902.1
Coordinates 64247..64555 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO76_RS16725 Protein ID WP_013209163.1
Coordinates 63945..64250 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO76_RS16685 59107..59517 + 411 WP_075465861.1 acyl-CoA thioesterase -
CJO76_RS16690 59555..59947 + 393 WP_075465862.1 RidA family protein -
CJO76_RS16695 60263..60544 - 282 WP_075465894.1 hypothetical protein -
CJO76_RS16700 60677..60961 - 285 WP_075465896.1 hypothetical protein -
CJO76_RS16710 61295..61597 + 303 Protein_53 transposase -
CJO76_RS16715 61648..62316 + 669 WP_075465898.1 hypothetical protein -
CJO76_RS16720 62421..63734 - 1314 WP_118884159.1 metabolite/H+ symporter -
CJO76_RS16725 63945..64250 - 306 WP_013209163.1 putative addiction module antidote protein Antitoxin
CJO76_RS16730 64247..64555 - 309 WP_075465902.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO76_RS16735 64640..65838 - 1199 Protein_58 MFS transporter -
CJO76_RS16740 65965..66780 - 816 WP_075465905.1 GntR family transcriptional regulator -
CJO76_RS16745 66954..67508 - 555 WP_118884160.1 helix-turn-helix transcriptional regulator -
CJO76_RS16750 67640..68236 + 597 WP_118884161.1 GNAT family N-acetyltransferase -
CJO76_RS16755 68492..68926 + 435 WP_013209169.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..1988531 1988531


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-85)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11795.54 Da        Isoelectric Point: 8.5237

>T79721 WP_075465902.1 NZ_CP022758:c64555-64247 [Ralstonia solanacearum]
MLTIRTTEIFDDWFCSLRDKAAQRRVQVRIDRLQMGNPGDVKAVREGIREMRIDHGPGYRVYFSQRGVVLIVLLCGGDKS
TQEADVRRAIDLSRRLDVDNME

Download         Length: 309 bp

>T79721 NZ_CP022758:c64555-64247 [Ralstonia solanacearum]
ATGCTGACAATCCGCACGACTGAAATCTTCGACGACTGGTTTTGCAGTCTCCGCGACAAGGCCGCGCAACGTCGCGTCCA
GGTGCGCATCGATCGCCTGCAGATGGGCAATCCAGGCGACGTGAAAGCTGTACGTGAAGGCATCCGTGAGATGCGGATCG
ATCATGGCCCGGGCTATCGCGTGTATTTTTCACAGCGTGGCGTGGTCCTGATCGTCCTGCTGTGCGGCGGTGACAAGTCG
ACGCAGGAAGCCGATGTCCGCCGCGCAATCGACCTGTCCCGCCGTCTTGACGTGGACAACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11009.67 Da        Isoelectric Point: 6.7174

>AT79721 WP_013209163.1 NZ_CP022758:c64250-63945 [Ralstonia solanacearum]
MMMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARARGMTQIARETGMTREGLYKALSEDGNP
SFATVLKVIRALGIRLHAVPA

Download         Length: 306 bp

>AT79721 NZ_CP022758:c64250-63945 [Ralstonia solanacearum]
ATGATGATGGCCCAACGCACCATAAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTATCTCGACGCCTGCCTGGAGGAAGCCGGGGATGACCCCGCATTCATCACGCACGCGCTGGGCGTGGTCGCGCGGGCGC
GCGGCATGACGCAGATCGCCCGCGAGACCGGGATGACGCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGACGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References