Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2215039..2215579 Replicon chromosome
Accession NZ_CP022757
Organism Ralstonia solanacearum strain T101

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CJO76_RS10235 Protein ID WP_048817440.1
Coordinates 2215039..2215299 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO76_RS10240 Protein ID WP_013212794.1
Coordinates 2215292..2215579 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO76_RS10215 2211172..2212089 - 918 WP_075464683.1 sugar ABC transporter substrate-binding protein -
CJO76_RS10220 2212300..2213352 - 1053 WP_118883343.1 LacI family DNA-binding transcriptional regulator -
CJO76_RS10225 2213487..2214635 + 1149 WP_118883344.1 fatty acid desaturase family protein -
CJO76_RS10230 2214601..2214912 + 312 WP_075464689.1 Rieske 2Fe-2S domain-containing protein -
CJO76_RS10235 2215039..2215299 + 261 WP_048817440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO76_RS10240 2215292..2215579 + 288 WP_013212794.1 putative addiction module antidote protein Antitoxin
CJO76_RS10245 2215592..2216437 - 846 WP_013212795.1 TIM barrel protein -
CJO76_RS10250 2216434..2217471 - 1038 WP_118883345.1 xylose isomerase -
CJO76_RS10255 2217468..2218757 - 1290 WP_118883346.1 FAD-dependent oxidoreductase -
CJO76_RS10260 2218924..2219841 + 918 WP_075464699.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9435.79 Da        Isoelectric Point: 10.3136

>T79720 WP_048817440.1 NZ_CP022757:2215039-2215299 [Ralstonia solanacearum]
MRDKRAKARIAARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGNKATQAQDIKQAIRMARDL
KESGHD

Download         Length: 261 bp

>T79720 NZ_CP022757:2215039-2215299 [Ralstonia solanacearum]
CTGCGCGACAAGCGTGCCAAGGCGCGGATCGCCGCCCGGCTGGTCAGCGCGTCGTTCGGAAATTTCGGCGACTGCAAGCC
GGTGGGTGAAGGCGTGAGCGAGATGCGGATCGATGTGGGCGCCGGGTATCGCGTCTACTACACGCGACAAGGTACTGTCG
TCTACATCCTGCTCACGGGCGGCAACAAGGCAACCCAAGCCCAGGACATCAAGCAAGCCATCCGGATGGCGCGCGACCTG
AAGGAGTCAGGCCATGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10022.45 Da        Isoelectric Point: 4.7361

>AT79720 WP_013212794.1 NZ_CP022757:2215292-2215579 [Ralstonia solanacearum]
MTETYAPFDAAAYLDSEETIAEFLAAAMEDPNPDVFLAALGAVARARGIAKVAADAGLGRESLYKAISPGAHPRYETIQK
IMRALGVRLNVTPAA

Download         Length: 288 bp

>AT79720 NZ_CP022757:2215292-2215579 [Ralstonia solanacearum]
ATGACTGAGACCTACGCACCGTTTGACGCGGCGGCCTACCTCGATAGCGAAGAGACCATCGCCGAATTTCTGGCGGCCGC
AATGGAAGACCCGAATCCGGATGTCTTCCTGGCTGCCCTCGGTGCCGTTGCGCGCGCCCGCGGCATTGCCAAGGTGGCTG
CGGACGCGGGCCTGGGGCGCGAAAGCCTGTACAAGGCCATCAGCCCCGGCGCGCACCCGCGCTACGAAACCATCCAGAAA
ATCATGCGCGCATTGGGCGTCAGGCTGAACGTGACGCCTGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References