Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 53076..53605 Replicon plasmid unnamed
Accession NZ_CP022756
Organism Ralstonia solanacearum strain T117

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CJO74_RS17690 Protein ID WP_016722340.1
Coordinates 53378..53605 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CJO74_RS17685 Protein ID WP_016722339.1
Coordinates 53076..53381 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJO74_RS17660 48454..49419 + 966 WP_016721735.1 IS5 family transposase -
CJO74_RS17665 49596..50420 + 825 WP_020830182.1 IS5 family transposase -
CJO74_RS17670 50459..50610 + 152 Protein_48 IS5/IS1182 family transposase -
CJO74_RS17675 50777..51445 + 669 WP_038938024.1 hypothetical protein -
CJO74_RS17680 51550..52863 - 1314 WP_038938025.1 metabolite/H+ symporter -
CJO74_RS17685 53076..53381 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
CJO74_RS17690 53378..53605 - 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CJO74_RS17695 53760..54959 - 1200 WP_016726513.1 MFS transporter -
CJO74_RS17700 55086..55907 - 822 WP_011003398.1 GntR family transcriptional regulator -
CJO74_RS17705 56085..56636 - 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
CJO74_RS17710 56769..57368 + 600 WP_118888101.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..2061886 2061886


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T79718 WP_016722340.1 NZ_CP022756:c53605-53378 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T79718 NZ_CP022756:c53605-53378 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT79718 WP_016722339.1 NZ_CP022756:c53381-53076 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT79718 NZ_CP022756:c53381-53076 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References