Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 3009608..3010143 Replicon chromosome
Accession NZ_CP022753
Organism Nocardiopsis gilva YIM 90087

Toxin (Protein)


Gene name relE Uniprot ID A0A223S6G9
Locus tag CDO52_RS13815 Protein ID WP_017616639.1
Coordinates 3009874..3010143 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A223S6G3
Locus tag CDO52_RS13810 Protein ID WP_017616640.1
Coordinates 3009608..3009877 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDO52_RS13795 3006151..3006477 - 327 WP_017616643.1 nuclear transport factor 2 family protein -
CDO52_RS13800 3006618..3008264 - 1647 WP_051060624.1 glycoside hydrolase family 13 protein -
CDO52_RS13805 3008425..3009579 + 1155 WP_094932426.1 glycosyltransferase family 4 protein -
CDO52_RS13810 3009608..3009877 + 270 WP_017616640.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CDO52_RS13815 3009874..3010143 + 270 WP_017616639.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CDO52_RS13820 3010304..3011458 + 1155 WP_017616638.1 acyl-CoA dehydrogenase family protein -
CDO52_RS13825 3011740..3012984 + 1245 WP_094932427.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
CDO52_RS13830 3012977..3014278 + 1302 WP_017616635.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-55)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10724.39 Da        Isoelectric Point: 11.1213

>T79715 WP_017616639.1 NZ_CP022753:3009874-3010143 [Nocardiopsis gilva YIM 90087]
VTSFRTRFHEEARRDLRKIPKRFAMTILRKLTNLQEDPYGCNSTAMVSRPERRRLRVGDYRVIYTVDNGELIIWVIEVGH
RSEIYKRRS

Download         Length: 270 bp

>T79715 NZ_CP022753:3009874-3010143 [Nocardiopsis gilva YIM 90087]
GTGACCTCCTTCCGCACCAGGTTTCACGAGGAGGCTCGGCGCGACCTCCGCAAGATCCCGAAGCGTTTCGCGATGACCAT
CCTCCGCAAACTCACAAACCTGCAGGAGGATCCTTACGGCTGCAACTCGACCGCCATGGTGTCACGGCCCGAGCGGCGTC
GGCTGAGGGTGGGCGACTATCGCGTGATCTACACGGTCGACAACGGAGAGTTGATCATCTGGGTGATCGAAGTCGGGCAT
CGATCGGAGATCTACAAACGTCGCTCGTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10077.33 Da        Isoelectric Point: 4.2057

>AT79715 WP_017616640.1 NZ_CP022753:3009608-3009877 [Nocardiopsis gilva YIM 90087]
MAEQLPSESIRDLRDHLSEVIDRVNSTESPTVITRRGKEVGAIIPIEALRQFLQWEEEQLNRIVDERMAEPGPGVPLEDV
IAETLARSE

Download         Length: 270 bp

>AT79715 NZ_CP022753:3009608-3009877 [Nocardiopsis gilva YIM 90087]
ATGGCAGAGCAACTTCCCAGCGAATCGATTCGCGATCTACGGGACCACCTGTCCGAAGTCATCGACCGGGTGAACTCCAC
CGAATCCCCGACGGTCATCACGCGTCGGGGAAAGGAAGTCGGAGCGATCATCCCCATCGAGGCGCTGCGCCAGTTCCTGC
AGTGGGAAGAGGAGCAGCTGAACCGGATCGTGGATGAGCGCATGGCCGAGCCGGGCCCCGGTGTGCCACTTGAGGACGTG
ATCGCAGAGACCCTGGCGAGGTCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A223S6G9

Antitoxin

Source ID Structure
AlphaFold DB A0A223S6G3

References