Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /BrnT(toxin) |
Location | 739514..740009 | Replicon | chromosome |
Accession | NZ_CP022742 | ||
Organism | Vibrio qinghaiensis strain Q67 |
Toxin (Protein)
Gene name | - | Uniprot ID | A0A7X5BHA6 |
Locus tag | CCZ37_RS17085 | Protein ID | WP_010320360.1 |
Coordinates | 739743..740009 (-) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | A0A223N3E7 |
Locus tag | CCZ37_RS17080 | Protein ID | WP_010320361.1 |
Coordinates | 739514..739756 (-) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CCZ37_RS17035 | 735706..736122 | - | 417 | WP_071187975.1 | hypothetical protein | - |
CCZ37_RS17040 | 736160..736276 | - | 117 | WP_094501664.1 | DUF3265 domain-containing protein | - |
CCZ37_RS17045 | 736267..736551 | - | 285 | WP_094501666.1 | antibiotic biosynthesis monooxygenase | - |
CCZ37_RS17065 | 738767..739069 | - | 303 | WP_094501670.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
CCZ37_RS17070 | 739057..739314 | - | 258 | WP_094501672.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
CCZ37_RS17075 | 739399..739533 | - | 135 | WP_081480767.1 | DUF3265 domain-containing protein | - |
CCZ37_RS17080 | 739514..739756 | - | 243 | WP_010320361.1 | hypothetical protein | Antitoxin |
CCZ37_RS17085 | 739743..740009 | - | 267 | WP_010320360.1 | BrnT family toxin | Toxin |
CCZ37_RS17090 | 740727..741281 | - | 555 | WP_088733336.1 | hypothetical protein | - |
CCZ37_RS17105 | 743483..743599 | - | 117 | WP_094502161.1 | DUF3265 domain-containing protein | - |
CCZ37_RS17110 | 743596..744594 | - | 999 | WP_094501674.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 665923..741281 | 75358 | |
- | inside | Integron | - | - | 721829..823951 | 102122 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10211.48 Da Isoelectric Point: 7.2007
>T79708 WP_010320360.1 NZ_CP022742:c740009-739743 [Vibrio qinghaiensis]
MTKFEFDENKSRSNFEKHGIDFYTAQGLWNDSDLIEIPANTSDEPRYLVIGMLNGKHWSGVITYRGLNIRIISVRRSRKA
EVNLYESA
MTKFEFDENKSRSNFEKHGIDFYTAQGLWNDSDLIEIPANTSDEPRYLVIGMLNGKHWSGVITYRGLNIRIISVRRSRKA
EVNLYESA
Download Length: 267 bp
>T79708 NZ_CP022742:c740009-739743 [Vibrio qinghaiensis]
ATGACGAAATTCGAATTTGATGAAAATAAAAGCAGGTCAAATTTTGAGAAACATGGAATTGATTTCTATACAGCTCAAGG
TTTGTGGAATGACTCTGATCTTATCGAGATCCCTGCAAACACAAGTGATGAACCTAGGTATTTGGTCATCGGCATGTTAA
ATGGTAAGCATTGGTCTGGCGTCATTACATACCGTGGACTAAATATTAGGATCATTTCAGTCAGACGTTCACGTAAAGCG
GAGGTGAACTTATATGAAAGCGCATGA
ATGACGAAATTCGAATTTGATGAAAATAAAAGCAGGTCAAATTTTGAGAAACATGGAATTGATTTCTATACAGCTCAAGG
TTTGTGGAATGACTCTGATCTTATCGAGATCCCTGCAAACACAAGTGATGAACCTAGGTATTTGGTCATCGGCATGTTAA
ATGGTAAGCATTGGTCTGGCGTCATTACATACCGTGGACTAAATATTAGGATCATTTCAGTCAGACGTTCACGTAAAGCG
GAGGTGAACTTATATGAAAGCGCATGA
Antitoxin
Download Length: 81 a.a. Molecular weight: 9358.60 Da Isoelectric Point: 6.8803
>AT79708 WP_010320361.1 NZ_CP022742:c739756-739514 [Vibrio qinghaiensis]
MKAHEFDAKFESDDDILGDLDLSKVKRPMQKQKRVNVDFPSWMLDSLDREANRVGVTRQSIIKIWLAERLENVAHHHTSN
MKAHEFDAKFESDDDILGDLDLSKVKRPMQKQKRVNVDFPSWMLDSLDREANRVGVTRQSIIKIWLAERLENVAHHHTSN
Download Length: 243 bp
>AT79708 NZ_CP022742:c739756-739514 [Vibrio qinghaiensis]
ATGAAAGCGCATGAGTTTGATGCCAAGTTTGAAAGTGACGATGACATTTTAGGTGATCTAGATTTATCTAAAGTTAAGCG
TCCAATGCAAAAGCAGAAACGGGTAAATGTTGATTTCCCCTCATGGATGTTAGATTCACTAGATCGTGAAGCTAACCGAG
TAGGTGTTACACGACAGTCGATTATCAAGATTTGGCTAGCTGAAAGGCTTGAAAATGTAGCTCATCACCACACTTCAAAC
TAA
ATGAAAGCGCATGAGTTTGATGCCAAGTTTGAAAGTGACGATGACATTTTAGGTGATCTAGATTTATCTAAAGTTAAGCG
TCCAATGCAAAAGCAGAAACGGGTAAATGTTGATTTCCCCTCATGGATGTTAGATTCACTAGATCGTGAAGCTAACCGAG
TAGGTGTTACACGACAGTCGATTATCAAGATTTGGCTAGCTGAAAGGCTTGAAAATGTAGCTCATCACCACACTTCAAAC
TAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7X5BHA6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A223N3E7 |