Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 739514..740009 Replicon chromosome
Accession NZ_CP022742
Organism Vibrio qinghaiensis strain Q67

Toxin (Protein)


Gene name - Uniprot ID A0A7X5BHA6
Locus tag CCZ37_RS17085 Protein ID WP_010320360.1
Coordinates 739743..740009 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A223N3E7
Locus tag CCZ37_RS17080 Protein ID WP_010320361.1
Coordinates 739514..739756 (-) Length 81 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCZ37_RS17035 735706..736122 - 417 WP_071187975.1 hypothetical protein -
CCZ37_RS17040 736160..736276 - 117 WP_094501664.1 DUF3265 domain-containing protein -
CCZ37_RS17045 736267..736551 - 285 WP_094501666.1 antibiotic biosynthesis monooxygenase -
CCZ37_RS17065 738767..739069 - 303 WP_094501670.1 type II toxin-antitoxin system RelE/ParE family toxin -
CCZ37_RS17070 739057..739314 - 258 WP_094501672.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
CCZ37_RS17075 739399..739533 - 135 WP_081480767.1 DUF3265 domain-containing protein -
CCZ37_RS17080 739514..739756 - 243 WP_010320361.1 hypothetical protein Antitoxin
CCZ37_RS17085 739743..740009 - 267 WP_010320360.1 BrnT family toxin Toxin
CCZ37_RS17090 740727..741281 - 555 WP_088733336.1 hypothetical protein -
CCZ37_RS17105 743483..743599 - 117 WP_094502161.1 DUF3265 domain-containing protein -
CCZ37_RS17110 743596..744594 - 999 WP_094501674.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 665923..741281 75358
- inside Integron - - 721829..823951 102122


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-81)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10211.48 Da        Isoelectric Point: 7.2007

>T79708 WP_010320360.1 NZ_CP022742:c740009-739743 [Vibrio qinghaiensis]
MTKFEFDENKSRSNFEKHGIDFYTAQGLWNDSDLIEIPANTSDEPRYLVIGMLNGKHWSGVITYRGLNIRIISVRRSRKA
EVNLYESA

Download         Length: 267 bp

>T79708 NZ_CP022742:c740009-739743 [Vibrio qinghaiensis]
ATGACGAAATTCGAATTTGATGAAAATAAAAGCAGGTCAAATTTTGAGAAACATGGAATTGATTTCTATACAGCTCAAGG
TTTGTGGAATGACTCTGATCTTATCGAGATCCCTGCAAACACAAGTGATGAACCTAGGTATTTGGTCATCGGCATGTTAA
ATGGTAAGCATTGGTCTGGCGTCATTACATACCGTGGACTAAATATTAGGATCATTTCAGTCAGACGTTCACGTAAAGCG
GAGGTGAACTTATATGAAAGCGCATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9358.60 Da        Isoelectric Point: 6.8803

>AT79708 WP_010320361.1 NZ_CP022742:c739756-739514 [Vibrio qinghaiensis]
MKAHEFDAKFESDDDILGDLDLSKVKRPMQKQKRVNVDFPSWMLDSLDREANRVGVTRQSIIKIWLAERLENVAHHHTSN

Download         Length: 243 bp

>AT79708 NZ_CP022742:c739756-739514 [Vibrio qinghaiensis]
ATGAAAGCGCATGAGTTTGATGCCAAGTTTGAAAGTGACGATGACATTTTAGGTGATCTAGATTTATCTAAAGTTAAGCG
TCCAATGCAAAAGCAGAAACGGGTAAATGTTGATTTCCCCTCATGGATGTTAGATTCACTAGATCGTGAAGCTAACCGAG
TAGGTGTTACACGACAGTCGATTATCAAGATTTGGCTAGCTGAAAGGCTTGAAAATGTAGCTCATCACCACACTTCAAAC
TAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7X5BHA6


Antitoxin

Source ID Structure
AlphaFold DB A0A223N3E7

References