Detailed information of TA system TA079707

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-Phd
• Location: 738767..739314
• Replicon: chromosome
• Accession: NZ_CP022742
• Organism: Vibrio qinghaiensis strain Q67

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CCZ37_RS17065
• Protein ID: WP_094501670.1
• Coordinates: 738767..739069 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CCZ37_RS17070
• Protein ID: WP_094501672.1
• Coordinates: 739057..739314 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCZ37_RS17035	735706..736122	-	417	WP_071187975.1	hypothetical protein	-
CCZ37_RS17040	736160..736276	-	117	WP_094501664.1	DUF3265 domain-containing protein	-
CCZ37_RS17045	736267..736551	-	285	WP_094501666.1	antibiotic biosynthesis monooxygenase	-
CCZ37_RS17065	738767..739069	-	303	WP_094501670.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CCZ37_RS17070	739057..739314	-	258	WP_094501672.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CCZ37_RS17075	739399..739533	-	135	WP_081480767.1	DUF3265 domain-containing protein	-
CCZ37_RS17080	739514..739756	-	243	WP_010320361.1	hypothetical protein	-
CCZ37_RS17085	739743..740009	-	267	WP_010320360.1	BrnT family toxin	-
CCZ37_RS17090	740727..741281	-	555	WP_088733336.1	hypothetical protein	-
CCZ37_RS17105	743483..743599	-	117	WP_094502161.1	DUF3265 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	665923..741281	75358
	-	inside	Integron	-	-	721829..823951	102122

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-66)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11728.55 Da
• Isoelectric Point: 5.1649

>T79707 WP_094501670.1 NZ_CP022742:c739069-738767 [Vibrio qinghaiensis]
MAEIIWTDPALSDLNDIAEYIALENVVSAKQLVQTIFSKVERLETFPDSGRIPPELEHLSYREVVINPCRVFYKQNDGKV
YILFVMRAERDLRKFLLNRQ

Nucleotide

• Length: 303 bp

>T79707 NZ_CP022742:c739069-738767 [Vibrio qinghaiensis]
ATGGCTGAAATAATTTGGACTGACCCAGCGTTATCAGATCTTAACGATATCGCTGAATATATAGCACTTGAAAATGTTGT
GTCTGCAAAACAATTAGTCCAAACGATTTTCTCTAAAGTTGAACGTTTGGAAACCTTTCCTGATTCAGGCCGTATCCCAC
CAGAACTCGAACATTTAAGTTACAGGGAAGTTGTTATTAATCCGTGTCGTGTTTTTTATAAACAAAATGACGGCAAGGTT
TATATTTTATTTGTTATGCGAGCAGAAAGAGATCTTCGTAAATTTTTGTTAAATAGACAATAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9656.21 Da
• Isoelectric Point: 8.5739

>AT79707 WP_094501672.1 NZ_CP022742:c739314-739057 [Vibrio qinghaiensis]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLIDVDDYEFMQNRLAILEGIARGERAITDGRVISHHEAKGKM
SKWLK

Nucleotide

• Length: 258 bp

>AT79707 NZ_CP022742:c739314-739057 [Vibrio qinghaiensis]
ATGAAAGTTGAATTGGTAACATCACTTAAGCGACAAGCAACTAAGATTCTTGCTGATCTTCATGATACCAAAGAGCCTGT
ATTAATCACTGAACATGGTAAACCATCGGCTTATCTTATTGATGTTGATGATTATGAGTTTATGCAAAATCGATTAGCGA
TTCTTGAAGGTATTGCTCGTGGTGAGCGAGCGATTACCGACGGTAGAGTAATTTCTCATCATGAAGCCAAGGGCAAAATG
TCAAAATGGCTGAAATAA