Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 703174..703712 Replicon chromosome
Accession NZ_CP022742
Organism Vibrio qinghaiensis strain Q67

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CCZ37_RS16810 Protein ID WP_094501630.1
Coordinates 703413..703712 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A223N3B0
Locus tag CCZ37_RS16805 Protein ID WP_072609711.1
Coordinates 703174..703416 (+) Length 81 a.a.

Genomic Context

CCZ37_RS16780CCZ37_RS16785CCZ37_RS16805CCZ37_RS16810CCZ37_RS16765CCZ37_RS16770CCZ37_RS16795CCZ37_RS16800CCZ37_RS16815CCZ37_RS16820CCZ37_RS16825CCZ37_RS16830CCZ37_RS16835CCZ37_RS16840
Location: 701552..701794 (243 bp)
Type: Others
Protein ID: WP_017045414.1
Location: 701791..702090 (300 bp)
Type: Others
Protein ID: WP_019282621.1
Location: 703174..703416 (243 bp)
Type: Antitoxin
Protein ID: WP_072609711.1
Location: 703413..703712 (300 bp)
Type: Toxin
Protein ID: WP_094501630.1
Location: 698931..699041 (111 bp)
Type: Others
Protein ID: WP_080115538.1
Location: 699038..699784 (747 bp)
Type: Others
Protein ID: WP_157729227.1
Location: 702212..702970 (759 bp)
Type: Others
Protein ID: WP_094501516.1
Location: 702998..703114 (117 bp)
Type: Others
Protein ID: WP_157729228.1
Location: 703839..704234 (396 bp)
Type: Others
Protein ID: WP_094182980.1
Location: 704385..705353 (969 bp)
Type: Others
Protein ID: WP_094501631.1
Location: 705382..705501 (120 bp)
Type: Others
Protein ID: WP_020977912.1
Location: 705526..705816 (291 bp)
Type: Others
Protein ID: WP_080536237.1
Location: 705858..706034 (177 bp)
Type: Others
Protein ID: Protein_616
Location: 706027..707148 (1122 bp)
Type: Others
Protein ID: WP_094501633.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CCZ37_RS16765698931..699041-111WP_080115538.1DUF3265 domain-containing protein-
CCZ37_RS16770699038..699784-747WP_157729227.1serine protease-
CCZ37_RS16780701552..701794+243WP_017045414.1type II toxin-antitoxin system ParD family antitoxin-
CCZ37_RS16785701791..702090+300WP_019282621.1type II toxin-antitoxin system RelE/ParE family toxin-
CCZ37_RS16795702212..702970-759WP_094501516.1hypothetical protein-
CCZ37_RS16800702998..703114-117WP_157729228.1DUF3265 domain-containing protein-
CCZ37_RS16805703174..703416+243WP_072609711.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
CCZ37_RS16810703413..703712+300WP_094501630.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CCZ37_RS16815703839..704234-396WP_094182980.1DUF3465 domain-containing protein-
CCZ37_RS16820704385..705353-969WP_094501631.1DUF4917 family protein-
CCZ37_RS16825705382..705501-120WP_020977912.1DUF3265 domain-containing protein-
CCZ37_RS16830705526..705816-291WP_080536237.1YkgJ family cysteine cluster protein-
CCZ37_RS16835705858..706034-177Protein_616DUF3265 domain-containing protein-
CCZ37_RS16840706027..707148-1122WP_094501633.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--665923..74128175358
-insideIntegron--569077..720478151401


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11661.43 Da        Isoelectric Point: 9.8917

>T79706 WP_094501630.1 NZ_CP022742:703413-703712 [Vibrio qinghaiensis]
MKPFQLTIKAKSDLKDIALFTSRRWGREQRNIYLKQFDESFWLLAENPDIGKTCDEIRDGYRKFPQGSHVIFYQQIGSQN
IQIIRILHKSMDVNPIFGA

Download         Length: 300 bp

>T79706 NZ_CP022742:703413-703712 [Vibrio qinghaiensis]
ATGAAACCATTCCAACTTACAATCAAGGCAAAATCCGATTTAAAAGATATTGCCTTATTTACCTCCCGTAGATGGGGGCG
AGAGCAGCGAAATATTTACCTAAAACAATTCGATGAGTCATTTTGGCTATTAGCTGAAAATCCTGACATTGGCAAAACTT
GTGATGAAATCAGAGATGGCTACCGAAAGTTTCCGCAAGGAAGCCATGTTATTTTTTATCAACAAATTGGTAGCCAAAAC
ATCCAGATAATTAGGATCTTGCATAAGAGTATGGATGTGAATCCAATCTTTGGCGCATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.91 Da        Isoelectric Point: 4.2340

>AT79706 WP_072609711.1 NZ_CP022742:703174-703416 [Vibrio qinghaiensis]
MAKNTSITLGEHFDGFISSQIQSGRYGSASEVIRSALRLLETQETKMNTLRQLLVEGEESGMADYDLDSFISELDSEERK

Download         Length: 243 bp

>AT79706 NZ_CP022742:703174-703416 [Vibrio qinghaiensis]
ATGGCTAAAAATACTAGCATTACTCTTGGTGAACATTTTGATGGCTTTATCAGTAGCCAGATCCAAAGTGGACGCTATGG
TTCAGCAAGTGAAGTGATTCGTTCAGCTTTACGTTTACTCGAAACACAAGAAACAAAAATGAACACGTTACGACAGCTAC
TCGTTGAAGGTGAAGAAAGTGGTATGGCTGATTATGACCTCGATTCGTTTATCAGTGAACTAGATAGCGAAGAGAGAAAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A223N3B0

References