Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 643471..644030 Replicon chromosome
Accession NZ_CP022742
Organism Vibrio qinghaiensis strain Q67

Toxin (Protein)


Gene name relE Uniprot ID F7YRQ7
Locus tag CCZ37_RS16410 Protein ID WP_010320663.1
Coordinates 643752..644030 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A233HRF0
Locus tag CCZ37_RS16405 Protein ID WP_017040620.1
Coordinates 643471..643755 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCZ37_RS16385 639243..640715 - 1473 WP_094501567.1 AAA family ATPase -
CCZ37_RS16405 643471..643755 + 285 WP_017040620.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CCZ37_RS16410 643752..644030 + 279 WP_010320663.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 631173..652812 21639
- inside Integron - - 569077..720478 151401


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10878.58 Da        Isoelectric Point: 4.3430

>T79704 WP_010320663.1 NZ_CP022742:643752-644030 [Vibrio qinghaiensis]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDDIIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGSIIRIM
RVLHQKQKFPTD

Download         Length: 279 bp

>T79704 NZ_CP022742:643752-644030 [Vibrio qinghaiensis]
ATGATTTTATGGGAAGAAGAATCGCTAAATGATCGTGAGAAGATCTTTGAGTTTCTTTATGACTTTAACCCTGATGCGGC
TGAAAAAACTGATGACATTATTGAGGCTAAAGTAGAAAACTTACTCGAACAACCATTGATGGGTGTTCAACGGGATGGAA
TTCGAGGACGATTACTCATTATTCCCGAAATCTCAATGATCGTTTCGTATTGGGTAGAAGGTTCAATTATTCGCATAATG
CGAGTTCTACACCAGAAGCAGAAATTCCCTACCGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10957.29 Da        Isoelectric Point: 9.2173

>AT79704 WP_017040620.1 NZ_CP022742:643471-643755 [Vibrio qinghaiensis]
MDTRIQFRVDDEIKRLAQQMAESQGRTLSDACRELTEQMAEQQRKTLSHDAWLTEQINLAFEKFDSGKSSFVEHNSAKAR
MAERKAKIRNRGQQ

Download         Length: 285 bp

>AT79704 NZ_CP022742:643471-643755 [Vibrio qinghaiensis]
ATGGACACTAGAATTCAATTTCGTGTTGATGACGAAATTAAACGTTTAGCCCAACAGATGGCTGAGAGCCAAGGCCGCAC
ACTCAGCGATGCTTGCCGTGAACTTACTGAACAAATGGCTGAGCAACAAAGAAAAACATTATCTCATGACGCTTGGTTAA
CTGAACAAATAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTTCATTTGTTGAACATAATTCAGCTAAAGCACGA
ATGGCTGAACGAAAGGCCAAAATTCGTAATCGAGGCCAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0F2IQF3

Antitoxin

Source ID Structure
AlphaFold DB A0A233HRF0

References