Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 635365..635912 Replicon chromosome
Accession NZ_CP022742
Organism Vibrio qinghaiensis strain Q67

Toxin (Protein)


Gene name relE Uniprot ID A0A223N2K4
Locus tag CCZ37_RS16360 Protein ID WP_000229324.1
Coordinates 635365..635667 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q9KM93
Locus tag CCZ37_RS16365 Protein ID WP_000861987.1
Coordinates 635655..635912 (-) Length 86 a.a.

Genomic Context

CCZ37_RS16375CCZ37_RS16330CCZ37_RS16335CCZ37_RS16340CCZ37_RS16345CCZ37_RS16350CCZ37_RS18935CCZ37_RS16360CCZ37_RS16365CCZ37_RS16385
Location: 636664..637632 (969 bp)
Type: Others
Protein ID: WP_094501484.1
Location: 631066..631182 (117 bp)
Type: Others
Protein ID: WP_094502140.1
Location: 631173..631856 (684 bp)
Type: Others
Protein ID: WP_094501561.1
Location: 631951..632523 (573 bp)
Type: Others
Protein ID: WP_094501563.1
Location: 634650..634769 (120 bp)
Type: Others
Protein ID: WP_208613968.1
Location: 634763..635209 (447 bp)
Type: Others
Protein ID: WP_000805118.1
Location: 635239..635355 (117 bp)
Type: Others
Protein ID: Protein_554
Location: 635365..635667 (303 bp)
Type: Toxin
Protein ID: WP_000229324.1
Location: 635655..635912 (258 bp)
Type: Antitoxin
Protein ID: WP_000861987.1
Location: 639243..640715 (1473 bp)
Type: Others
Protein ID: WP_094501567.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CCZ37_RS16330631066..631182-117WP_094502140.1DUF3265 domain-containing protein-
CCZ37_RS16335631173..631856-684WP_094501561.1hypothetical protein-
CCZ37_RS16340631951..632523-573WP_094501563.1hypothetical protein-
CCZ37_RS16345634650..634769-120WP_208613968.1DUF3265 domain-containing protein-
CCZ37_RS16350634763..635209-447WP_000805118.1hypothetical protein-
CCZ37_RS18935635239..635355-117Protein_554DUF3265 domain-containing protein-
CCZ37_RS16360635365..635667-303WP_000229324.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CCZ37_RS16365635655..635912-258WP_000861987.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
CCZ37_RS16375636664..637632+969WP_094501484.1IS30 family transposase-
CCZ37_RS16385639243..640715-1473WP_094501567.1AAA family ATPase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--631173..65281221639
-flankIS/Tn--636664..637632968
-insideIntegron--569077..720478151401


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11795.70 Da        Isoelectric Point: 4.9166

>T79703 WP_000229324.1 NZ_CP022742:c635667-635365 [Vibrio qinghaiensis]
MVEIIWTEPALSDLNDIAEYIALENVVAAKQLVQTVFTKVERLADFPESGRVPPELEHLNYREVVVNPCRVFYKYDDEKV
RILFVMRAERDLRRLMLTKQ

Download         Length: 303 bp

>T79703 NZ_CP022742:c635667-635365 [Vibrio qinghaiensis]
ATGGTTGAAATAATTTGGACGGAGCCGGCTCTATCCGATCTGAATGATATTGCTGAATACATCGCACTTGAAAATGTCGT
GGCTGCTAAACAACTGGTGCAAACCGTGTTTACAAAAGTTGAACGTTTGGCCGATTTTCCAGAGTCTGGGCGCGTCCCAC
CAGAACTAGAACACCTCAATTATCGTGAAGTCGTTGTAAATCCGTGTCGTGTTTTCTACAAGTATGATGATGAAAAGGTT
CGTATTCTTTTTGTTATGCGTGCGGAGCGAGATTTGCGTCGCTTAATGCTAACGAAACAGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9647.15 Da        Isoelectric Point: 7.3178

>AT79703 WP_000861987.1 NZ_CP022742:c635912-635655 [Vibrio qinghaiensis]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLIDVDDYEFMQNRLAILEGIARGERALADGKVVSHQDAKDRM
SKWLK

Download         Length: 258 bp

>AT79703 NZ_CP022742:c635912-635655 [Vibrio qinghaiensis]
ATGAAAGTAGAACTCGTGACGTCACTAAAACGGCAGGCCACTAAGATCCTTGCCGATCTTCATGATACGAAAGAACCAGT
ATTGATAACTGAGCACGGAAAGCCGTCAGCTTACCTTATTGATGTAGATGATTATGAATTTATGCAAAATCGTCTAGCGA
TCCTCGAAGGCATTGCTCGTGGCGAACGAGCTCTAGCGGATGGCAAAGTGGTCAGCCATCAAGATGCTAAGGATAGAATG
TCAAAATGGTTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A223N2K4

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1T4SLM9

References