Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 399983..400533 Replicon chromosome
Accession NZ_CP022741
Organism Vibrio qinghaiensis strain Q67

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CCZ37_RS02015 Protein ID WP_094499622.1
Coordinates 399983..400282 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A223MVC0
Locus tag CCZ37_RS02020 Protein ID WP_010318194.1
Coordinates 400291..400533 (-) Length 81 a.a.

Genomic Context

CCZ37_RS02000CCZ37_RS02005CCZ37_RS02035CCZ37_RS02010CCZ37_RS02015CCZ37_RS02020CCZ37_RS02025CCZ37_RS02030
Location: 395184..395945 (762 bp)
Type: Others
Protein ID: WP_010318405.1
Location: 396031..397863 (1833 bp)
Type: Others
Protein ID: WP_094499620.1
Location: 403535..404053 (519 bp)
Type: Others
Protein ID: WP_010318197.1
Location: 398235..399587 (1353 bp)
Type: Others
Protein ID: WP_094499621.1
Location: 399983..400282 (300 bp)
Type: Toxin
Protein ID: WP_094499622.1
Location: 400291..400533 (243 bp)
Type: Antitoxin
Protein ID: WP_010318194.1
Location: 400688..402439 (1752 bp)
Type: Others
Protein ID: WP_094499623.1
Location: 402819..403232 (414 bp)
Type: Others
Protein ID: WP_010318196.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CCZ37_RS02000395184..395945+762WP_010318405.1DeoR family transcriptional regulator-
CCZ37_RS02005396031..397863+1833WP_094499620.1glutamine--fructose-6-phosphate transaminase (isomerizing)-
CCZ37_RS02010398235..399587-1353WP_094499621.1Fic family protein-
CCZ37_RS02015399983..400282-300WP_094499622.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CCZ37_RS02020400291..400533-243WP_010318194.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
CCZ37_RS02025400688..402439-1752WP_094499623.1lysophospholipid acyltransferase family protein-
CCZ37_RS02030402819..403232-414WP_010318196.1aminoacyl-tRNA hydrolase-
CCZ37_RS02035403535..404053+519WP_010318197.1Hcp family type VI secretion system effector-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-47)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11371.90 Da        Isoelectric Point: 9.3491

>T79699 WP_094499622.1 NZ_CP022741:c400282-399983 [Vibrio qinghaiensis]
MHNSEYKLSKLAQAHLHKIKNYTVTNFSEMQWNAYKDTLLTGFQMLADNPAVGRSCNDSYQNGFYFPIGKHTAYFTKENS
FILVVAVLGQSQLPQNHLR

Download         Length: 300 bp

>T79699 NZ_CP022741:c400282-399983 [Vibrio qinghaiensis]
ATGCACAATAGTGAATATAAACTAAGTAAATTAGCACAGGCTCATTTACATAAAATCAAAAATTATACCGTTACAAACTT
TTCCGAGATGCAGTGGAACGCATACAAAGACACTCTTCTTACTGGGTTTCAGATGCTCGCTGACAACCCAGCGGTAGGCA
GAAGCTGCAACGATTCATATCAAAATGGTTTTTACTTCCCTATAGGCAAGCATACGGCTTACTTTACCAAGGAAAACAGT
TTTATTTTGGTCGTTGCAGTCCTTGGACAATCGCAATTGCCACAAAACCATCTGCGATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9021.27 Da        Isoelectric Point: 5.0642

>AT79699 WP_010318194.1 NZ_CP022741:c400533-400291 [Vibrio qinghaiensis]
MYTLTANDAKRNFGELLLNAQREPVKISKNNKDAVVVMSIRDYEELEVMKADYIKHCFESAKADLAQGNVVNGENFLNAL

Download         Length: 243 bp

>AT79699 NZ_CP022741:c400533-400291 [Vibrio qinghaiensis]
ATGTACACATTAACAGCAAATGATGCCAAACGTAATTTCGGTGAACTGCTTTTAAACGCTCAACGTGAGCCAGTTAAAAT
TAGTAAAAACAATAAAGATGCCGTTGTTGTGATGTCGATTAGAGACTATGAAGAACTTGAAGTCATGAAAGCCGATTACA
TAAAACATTGTTTTGAGTCCGCAAAAGCAGACTTAGCCCAAGGCAATGTAGTTAACGGTGAAAACTTCCTAAACGCGTTG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A223MVC0

References