Detailed information of TA system TA079699

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 399983..400533
• Replicon: chromosome
• Accession: NZ_CP022741
• Organism: Vibrio qinghaiensis strain Q67

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: CCZ37_RS02015
• Protein ID: WP_094499622.1
• Coordinates: 399983..400282 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A223MVC0
• Locus tag: CCZ37_RS02020
• Protein ID: WP_010318194.1
• Coordinates: 400291..400533 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCZ37_RS02000	395184..395945	+	762	WP_010318405.1	DeoR family transcriptional regulator	-
CCZ37_RS02005	396031..397863	+	1833	WP_094499620.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
CCZ37_RS02010	398235..399587	-	1353	WP_094499621.1	Fic family protein	-
CCZ37_RS02015	399983..400282	-	300	WP_094499622.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CCZ37_RS02020	400291..400533	-	243	WP_010318194.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CCZ37_RS02025	400688..402439	-	1752	WP_094499623.1	lysophospholipid acyltransferase family protein	-
CCZ37_RS02030	402819..403232	-	414	WP_010318196.1	aminoacyl-tRNA hydrolase	-
CCZ37_RS02035	403535..404053	+	519	WP_010318197.1	Hcp family type VI secretion system effector	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-93)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-47)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11371.90 Da
• Isoelectric Point: 9.3491

>T79699 WP_094499622.1 NZ_CP022741:c400282-399983 [Vibrio qinghaiensis]
MHNSEYKLSKLAQAHLHKIKNYTVTNFSEMQWNAYKDTLLTGFQMLADNPAVGRSCNDSYQNGFYFPIGKHTAYFTKENS
FILVVAVLGQSQLPQNHLR

Nucleotide

• Length: 300 bp

>T79699 NZ_CP022741:c400282-399983 [Vibrio qinghaiensis]
ATGCACAATAGTGAATATAAACTAAGTAAATTAGCACAGGCTCATTTACATAAAATCAAAAATTATACCGTTACAAACTT
TTCCGAGATGCAGTGGAACGCATACAAAGACACTCTTCTTACTGGGTTTCAGATGCTCGCTGACAACCCAGCGGTAGGCA
GAAGCTGCAACGATTCATATCAAAATGGTTTTTACTTCCCTATAGGCAAGCATACGGCTTACTTTACCAAGGAAAACAGT
TTTATTTTGGTCGTTGCAGTCCTTGGACAATCGCAATTGCCACAAAACCATCTGCGATAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9021.27 Da
• Isoelectric Point: 5.0642

>AT79699 WP_010318194.1 NZ_CP022741:c400533-400291 [Vibrio qinghaiensis]
MYTLTANDAKRNFGELLLNAQREPVKISKNNKDAVVVMSIRDYEELEVMKADYIKHCFESAKADLAQGNVVNGENFLNAL

Nucleotide

• Length: 243 bp

>AT79699 NZ_CP022741:c400533-400291 [Vibrio qinghaiensis]
ATGTACACATTAACAGCAAATGATGCCAAACGTAATTTCGGTGAACTGCTTTTAAACGCTCAACGTGAGCCAGTTAAAAT
TAGTAAAAACAATAAAGATGCCGTTGTTGTGATGTCGATTAGAGACTATGAAGAACTTGAAGTCATGAAAGCCGATTACA
TAAAACATTGTTTTGAGTCCGCAAAAGCAGACTTAGCCCAAGGCAATGTAGTTAACGGTGAAAACTTCCTAAACGCGTTG
TAA

Structures

Antitoxin

• AlphaFold DB: A0A223MVC0