Detailed information of TA system TA079609

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 126882..127264
• Replicon: plasmid pAtBDGP1A
• Accession: NZ_CP022700
• Organism: Acetobacter tropicalis strain BDGP1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CIW82_RS19585
• Protein ID: WP_167385526.1
• Coordinates: 126882..127037 (-)
• Length: 52 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CIW82_RS19590
• Protein ID: WP_045543213.1
• Coordinates: 127022..127264 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CIW82_RS18800	121939..122217	+	279	WP_064776546.1	DUF2312 domain-containing protein	-
CIW82_RS18815	122972..124291	+	1320	WP_086897480.1	replication protein C	-
CIW82_RS18820	124382..124738	+	357	WP_176373080.1	hypothetical protein	-
CIW82_RS18825	124735..125781	+	1047	WP_097802574.1	Fic family protein	-
CIW82_RS18830	125794..126879	-	1086	WP_086898809.1	hypothetical protein	-
CIW82_RS19585	126882..127037	-	156	WP_167385526.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CIW82_RS19590	127022..127264	-	243	WP_045543213.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
CIW82_RS18845	128539..129732	-	1194	WP_157772984.1	HAMP domain-containing histidine kinase	-
CIW82_RS18850	129734..130915	-	1182	WP_086898530.1	sigma-54 dependent transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..151013	151013

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-39)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-61)

Sequences

Toxin

Protein

• Length: 52 a.a.
• Molecular weight: 5827.75 Da
• Isoelectric Point: 10.5191

>T79609 WP_167385526.1 NZ_CP022700:c127037-126882 [Acetobacter tropicalis]
IGRSVSCYKIKRRASGYRLVYQVNEGKLIVLVVAIGRRDANEVYDDATRRV

Nucleotide

• Length: 156 bp

>T79609 NZ_CP022700:c127037-126882 [Acetobacter tropicalis]
ATTGGACGATCTGTGAGCTGCTATAAAATCAAACGTCGAGCATCCGGATATCGGCTGGTGTATCAGGTTAATGAGGGGAA
ACTCATAGTGCTGGTTGTTGCGATTGGACGCAGGGATGCCAATGAGGTTTACGACGATGCAACCCGCCGCGTCTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8854.13 Da
• Isoelectric Point: 4.3951

>AT79609 WP_045543213.1 NZ_CP022700:c127264-127022 [Acetobacter tropicalis]
MASINLRIDDSLKKAAYDRLSELGVTPSDLIRQTFEYVVATGKLPVRRTVVSDDDLELLAVVRERLASPEPSIPVSLDDL

Nucleotide

• Length: 243 bp

>AT79609 NZ_CP022700:c127264-127022 [Acetobacter tropicalis]
ATGGCTTCAATTAACCTGCGCATCGATGACAGTCTGAAGAAAGCTGCATACGATCGTCTGTCAGAACTCGGTGTGACCCC
GTCTGACCTCATTCGCCAGACATTTGAATATGTCGTCGCCACAGGCAAGCTCCCCGTCCGGCGCACTGTTGTATCGGATG
ACGATCTGGAGCTCCTTGCCGTCGTTCGGGAGCGTCTTGCCTCGCCTGAACCGTCTATTCCGGTCTCATTGGACGATCTG
TGA