Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 369269..369852 Replicon chromosome
Accession NZ_CP022699
Organism Acetobacter tropicalis strain BDGP1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CIW82_RS01725 Protein ID WP_086897922.1
Coordinates 369269..369613 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CIW82_RS01730 Protein ID WP_086897921.1
Coordinates 369610..369852 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIW82_RS01700 364423..365265 - 843 WP_086898019.1 DUF3800 domain-containing protein -
CIW82_RS01705 365803..366993 - 1191 WP_053323893.1 IS91 family transposase -
CIW82_RS01710 367013..367924 - 912 WP_006560376.1 tyrosine-type recombinase/integrase -
CIW82_RS01715 367996..368292 - 297 WP_140385849.1 hypothetical protein -
CIW82_RS01720 368297..368995 - 699 WP_097802320.1 hypothetical protein -
CIW82_RS01725 369269..369613 - 345 WP_086897922.1 endoribonuclease MazF Toxin
CIW82_RS01730 369610..369852 - 243 WP_086897921.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CIW82_RS01735 370111..371133 + 1023 Protein_335 integrase -
CIW82_RS01740 371227..371787 + 561 WP_097802517.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 362667..389215 26548


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(13-112)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12562.71 Da        Isoelectric Point: 9.9545

>T79606 WP_086897922.1 NZ_CP022699:c369613-369269 [Acetobacter tropicalis]
VSAKAKTAWVPDCGEIVWLEFDPQAGREQAGHRPAVVLSPVSYNAKAGMMLCCPTTTKIKGYPFEVALTGKTASVALSDQ
VRSLDWRVRKAKLKDKVLPEELEAIRQRIRLLVG

Download         Length: 345 bp

>T79606 NZ_CP022699:c369613-369269 [Acetobacter tropicalis]
GTGAGTGCCAAAGCAAAGACTGCCTGGGTTCCTGATTGCGGGGAGATTGTCTGGCTTGAGTTTGATCCGCAGGCGGGCAG
GGAACAGGCTGGGCACCGACCTGCTGTTGTGCTGAGTCCTGTCAGCTATAACGCTAAAGCTGGAATGATGCTGTGCTGTC
CGACAACGACCAAGATCAAAGGCTATCCTTTTGAAGTGGCTCTGACTGGAAAAACTGCCAGTGTAGCCTTGTCAGATCAG
GTGAGAAGTTTGGATTGGCGCGTTAGAAAGGCAAAGCTCAAGGATAAAGTTTTACCAGAAGAACTTGAGGCCATCCGACA
GCGTATCAGATTGCTAGTCGGGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8807.10 Da        Isoelectric Point: 4.3085

>AT79606 WP_086897921.1 NZ_CP022699:c369852-369610 [Acetobacter tropicalis]
MQGVVRKWGNSAAIRLPAGVLEAVSLKIDQAVDVWEEDGRIIIEPVRAVPLKLEELVSGITVENRHDEMDFGPSIGGEIW

Download         Length: 243 bp

>AT79606 NZ_CP022699:c369852-369610 [Acetobacter tropicalis]
ATGCAGGGCGTTGTCAGGAAATGGGGGAACAGTGCAGCCATTCGTCTTCCTGCTGGTGTGCTTGAAGCCGTCAGTCTGAA
GATCGATCAGGCAGTCGATGTGTGGGAAGAAGATGGGCGGATTATTATCGAACCAGTCAGAGCAGTTCCTCTCAAACTGG
AAGAATTAGTGTCAGGTATTACGGTCGAGAACCGCCATGATGAAATGGACTTCGGTCCATCTATTGGCGGTGAAATCTGG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References