Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014279..2014424 Replicon chromosome
Accession NZ_CP022691
Organism Klebsiella pneumoniae subsp. pneumoniae strain AUSMDU00008079

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014315..2014417 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014279..2014424 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CI103_RS09775 2009409..2011469 + 2061 WP_032422099.1 oligopeptidase B -
CI103_RS09780 2011473..2012132 - 660 WP_002911407.1 exodeoxyribonuclease X -
CI103_RS09785 2012211..2012441 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CI103_RS09790 2012554..2012928 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CI103_RS09795 2012932..2013801 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
CI103_RS09800 2013818..2014156 + 339 WP_002911404.1 YebY family protein -
- 2014279..2014424 - 146 - - Antitoxin
- 2014315..2014417 + 103 - - Toxin
CI103_RS09805 2014792..2014935 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CI103_RS09810 2015040..2016008 - 969 WP_004151446.1 VirK/YbjX family protein -
CI103_RS09815 2016165..2016818 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
CI103_RS09820 2016815..2017006 - 192 WP_002911395.1 YebW family protein -
CI103_RS09825 2017104..2017343 - 240 WP_002911393.1 YebV family protein -
CI103_RS09830 2017459..2018892 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T79590 NZ_CP022691:2014315-2014417 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT79590 NZ_CP022691:c2014424-2014279 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References