Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4191934..4192205 Replicon chromosome
Accession NZ_CP022689
Organism Escherichia coli strain CDC#03-98

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4192064..4192167 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4191934..4192205 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RM34_RS22180 4188489..4189151 - 663 WP_000944243.1 exodeoxyribonuclease X -
RM34_RS22185 4189175..4189831 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
RM34_RS22190 4189933..4190163 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RM34_RS22195 4190302..4190676 + 375 WP_000168751.1 CopC domain-containing protein YobA -
RM34_RS22200 4190680..4191552 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
RM34_RS22205 4191565..4191906 + 342 WP_000976483.1 YebY family protein -
- 4191934..4192205 - 272 - - Antitoxin
- 4192064..4192167 + 104 - - Toxin
RM34_RS22210 4192302..4192958 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
RM34_RS22215 4192959..4193150 - 192 WP_001296140.1 YebW family protein -
RM34_RS22220 4193255..4193491 - 237 WP_001295499.1 DUF1480 family protein -
RM34_RS22225 4193609..4195048 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T79571 NZ_CP022689:4192064-4192167 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT79571 NZ_CP022689:c4192205-4191934 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References