Detailed information of TA system TA079507

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): TsaAT/-
• Location: 849145..849622
• Replicon: chromosome
• Accession: NZ_CP022682
• Organism: Staphylococcus aureus strain 78

Toxin (Protein)

• Gene name: TsaT
• Uniprot ID: -
• Locus tag: CGP84_RS04265
• Protein ID: WP_115288365.1
• Coordinates: 849145..849333 (-)
• Length: 63 a.a.

Antitoxin (Protein)

• Gene name: TsaA
• Uniprot ID: T1Y6P8
• Locus tag: CGP84_RS04270
• Protein ID: WP_001059690.1
• Coordinates: 849362..849622 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CGP84_RS04235	845173..845655	+	483	WP_000824492.1	hypothetical protein	-
CGP84_RS04240	845996..846682	+	687	WP_000141556.1	thermonuclease family protein	-
CGP84_RS04245	847039..847239	+	201	WP_001059082.1	cold-shock protein	-
CGP84_RS04250	847736..847954	-	219	WP_000005883.1	hypothetical protein	-
CGP84_RS04255	848016..848300	-	285	WP_001004397.1	hypothetical protein	-
CGP84_RS04260	848388..848957	-	570	WP_001106648.1	hypothetical protein	-
CGP84_RS04265	849145..849333	-	189	WP_115288365.1	hypothetical protein	Toxin
CGP84_RS04270	849362..849622	-	261	WP_001059690.1	hypothetical protein	Antitoxin
CGP84_RS04275	849963..850166	+	204	WP_000145163.1	sterile alpha motif-like domain-containing protein	-
CGP84_RS04280	850163..850399	-	237	WP_000368687.1	hypothetical protein	-
CGP84_RS04285	850624..851205	+	582	WP_001140691.1	phosphoglycerate mutase family protein	-
CGP84_RS04290	851278..851895	-	618	WP_047213256.1	LysE/ArgO family amino acid transporter	-
CGP84_RS04295	852052..852546	-	495	WP_000569881.1	GNAT family N-acetyltransferase	-
CGP84_RS04300	852945..853367	-	423	WP_031927537.1	organic hydroperoxide resistance protein	-
CGP84_RS04305	853515..854231	+	717	WP_031927536.1	type I 3-dehydroquinate dehydratase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 63 a.a.
• Molecular weight: 7128.75 Da
• Isoelectric Point: 9.6276

>T79507 WP_115288365.1 NZ_CP022682:c849333-849145 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKNTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Nucleotide

• Length: 189 bp

>T79507 NZ_CP022682:c849333-849145 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAATACTGGCAAAGAATCTAAAAAAGAATCCTATTTAAGTTTCACTGTCATTCTCTATATTTTCGGATTCGCTATTTTAA
TATACACATTTATATTTGGTGTACTATAA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9940.09 Da
• Isoelectric Point: 4.0624

>AT79507 WP_001059690.1 NZ_CP022682:c849622-849362 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Nucleotide

• Length: 261 bp

>AT79507 NZ_CP022682:c849622-849362 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATTGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A0E0VN56