Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2120581..2120815 Replicon chromosome
Accession NZ_CP022672
Organism Shigella sonnei strain 866

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2120711..2120814 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2120581..2120815 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CH310_RS10575 2117136..2117798 - 663 WP_000944256.1 exodeoxyribonuclease X -
CH310_RS10580 2117822..2118478 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
CH310_RS10585 2118580..2118810 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CH310_RS10590 2118949..2119323 + 375 WP_000168735.1 CopC domain-containing protein YobA -
CH310_RS10595 2119327..2120199 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
CH310_RS10600 2120212..2120553 + 342 WP_000976476.1 YebY family protein -
- 2120581..2120815 - 235 - - Antitoxin
- 2120711..2120814 + 104 - - Toxin
CH310_RS10605 2120946..2122022 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
CH310_RS10610 2122059..2122304 - 246 Protein_2037 IS1 family transposase -
CH310_RS10620 2123638..2124092 - 455 Protein_2039 IS1-like element IS1A family transposase -
CH310_RS10625 2124121..2124381 - 261 WP_077447296.1 excisionase -
CH310_RS10630 2124526..2125577 + 1052 Protein_2041 IS3-like element IS600 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T79490 NZ_CP022672:2120711-2120814 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT79490 NZ_CP022672:c2120815-2120581 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References