Detailed information of TA system TA079451

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 234272..234807
• Replicon: plasmid pRM11060-2
• Accession: NZ_CP022660
• Organism: Salmonella enterica subsp. enterica strain RM11060

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CGA23_RS26815
• Protein ID: WP_097361649.1
• Coordinates: 234520..234807 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CGA23_RS26810
• Protein ID: WP_057394760.1
• Coordinates: 234272..234523 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CGA23_RS26775	229898..230443	+	546	WP_057395076.1	phospholipase D family protein	-
CGA23_RS26780	230581..230838	+	258	WP_057395075.1	replication regulatory protein RepA	-
CGA23_RS26785	231070..231144	+	75	WP_071529947.1	RepA leader peptide Tap	-
CGA23_RS26790	231137..232153	+	1017	WP_097361647.1	replication initiation protein	-
CGA23_RS26800	233029..233421	-	393	WP_097361648.1	nuclear transport factor 2 family protein	-
CGA23_RS26805	233912..234194	-	283	Protein_259	hypothetical protein	-
CGA23_RS26810	234272..234523	+	252	WP_057394760.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CGA23_RS26815	234520..234807	+	288	WP_097361649.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CGA23_RS26820	234812..235042	+	231	WP_057394395.1	hypothetical protein	-
CGA23_RS26825	235198..235440	+	243	WP_057394396.1	hypothetical protein	-
CGA23_RS26830	235558..235803	-	246	Protein_264	hypothetical protein	-
CGA23_RS26835	236095..237672	+	1578	WP_079953194.1	hypothetical protein	-
CGA23_RS26840	237722..238252	-	531	WP_071497240.1	colicin immunity protein Cui	-
CGA23_RS26845	238311..238742	-	432	WP_057393438.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..290957	290957

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Cro/C1-type helix-turn-helix domain (49-93)

Antitoxin

• Toxin HigB-like (13-87)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 12322.73 Da
• Isoelectric Point: 12.7777

>T79451 WP_097361649.1 NZ_CP022660:234520-234807 [Salmonella enterica subsp. enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKK

Nucleotide

• Length: 288 bp

>T79451 NZ_CP022660:234520-234807 [Salmonella enterica subsp. enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 10784.64 Da
• Isoelectric Point: 12.7191

>AT79451 WP_057394760.1 NZ_CP022660:234272-234523 [Salmonella enterica subsp. enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Nucleotide

• Length: 252 bp

>AT79451 NZ_CP022660:234272-234523 [Salmonella enterica subsp. enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA