Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PrpT-parD/ParE-RHH
Location 164526..165051 Replicon plasmid pRM11060-2
Accession NZ_CP022660
Organism Salmonella enterica subsp. enterica strain RM11060

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag CGA23_RS26335 Protein ID WP_079953242.1
Coordinates 164526..164816 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CGA23_RS26340 Protein ID WP_057394653.1
Coordinates 164809..165051 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGA23_RS26310 159750..160055 - 306 WP_057394657.1 antibiotic biosynthesis monooxygenase -
CGA23_RS26315 160132..161025 - 894 WP_153789529.1 hypothetical protein -
CGA23_RS26320 161049..162239 - 1191 WP_097361620.1 MFS transporter -
CGA23_RS26325 162251..163357 - 1107 WP_097361621.1 ThiF family adenylyltransferase -
CGA23_RS26330 163603..164277 + 675 WP_057394654.1 metalloregulator ArsR/SmtB family transcription factor -
CGA23_RS26335 164526..164816 - 291 WP_079953242.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CGA23_RS26340 164809..165051 - 243 WP_057394653.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
CGA23_RS26345 165312..166277 + 966 WP_057394652.1 DNA-binding protein -
CGA23_RS26350 166364..167131 + 768 WP_097361665.1 3'-5' exonuclease -
CGA23_RS26355 167810..168898 - 1089 WP_097361622.1 transcriptional regulator -
CGA23_RS26360 169610..169828 + 219 WP_079953237.1 type II toxin-antitoxin system antitoxin CcdA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..290957 290957


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(18-97)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 14294.15 Da        Isoelectric Point: 5.5500

>T79448 WP_079953242.1 NZ_CP022660:c164816-164526 [Salmonella enterica subsp. enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFF

Download         Length: 291 bp

>T79448 NZ_CP022660:c164816-164526 [Salmonella enterica subsp. enterica]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 11939.32 Da        Isoelectric Point: 5.5500

>AT79448 WP_057394653.1 NZ_CP022660:c165051-164809 [Salmonella enterica subsp. enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F

Download         Length: 243 bp

>AT79448 NZ_CP022660:c165051-164809 [Salmonella enterica subsp. enterica]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References