Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5181718..5181863 Replicon chromosome
Accession NZ_CP022611
Organism Klebsiella pneumoniae strain CDC 0106

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5181754..5181856 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5181718..5181863 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHC10_RS25885 5176848..5178908 + 2061 WP_004151449.1 oligopeptidase B -
CHC10_RS25890 5178912..5179571 - 660 WP_043906809.1 exodeoxyribonuclease X -
CHC10_RS25895 5179650..5179880 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CHC10_RS25900 5179993..5180367 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CHC10_RS25905 5180371..5181240 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
CHC10_RS25910 5181257..5181595 + 339 WP_002911404.1 YebY family protein -
- 5181718..5181863 - 146 - - Antitoxin
- 5181754..5181856 + 103 - - Toxin
CHC10_RS30380 5182232..5182375 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CHC10_RS25920 5182480..5183448 - 969 WP_004151446.1 VirK/YbjX family protein -
CHC10_RS25925 5183605..5184257 + 653 Protein_4908 protein-serine/threonine phosphatase -
CHC10_RS25930 5184254..5184445 - 192 WP_002911395.1 YebW family protein -
CHC10_RS25935 5184543..5184782 - 240 WP_002911393.1 YebV family protein -
CHC10_RS25940 5184898..5186331 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T79428 NZ_CP022611:5181754-5181856 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT79428 NZ_CP022611:c5181863-5181718 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References