Detailed information of TA system TA079402

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 766931..767484
• Replicon: plasmid unnamed1
• Accession: NZ_CP022605
• Organism: [Ochrobactrum] quorumnocens strain A44

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CES85_RS25840
• Protein ID: WP_095448619.1
• Coordinates: 766931..767224 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CES85_RS25845
• Protein ID: WP_095448620.1
• Coordinates: 767212..767484 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CES85_RS25820	762872..763708	-	837	WP_095448616.1	ABC transporter permease	-
CES85_RS25825	763705..764739	-	1035	WP_095448875.1	ABC transporter permease	-
CES85_RS25830	764910..766505	-	1596	WP_095448617.1	ABC transporter substrate-binding protein	-
CES85_RS25840	766931..767224	-	294	WP_095448619.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CES85_RS25845	767212..767484	-	273	WP_095448620.1	CopG family ribbon-helix-helix protein	Antitoxin
CES85_RS25850	767931..768221	-	291	WP_095448621.1	putative addiction module antidote protein	-
CES85_RS25855	768214..768524	-	311	Protein_725	type II toxin-antitoxin system RelE/ParE family toxin	-
CES85_RS25860	768631..768903	-	273	WP_095445719.1	MarR family transcriptional regulator	-
CES85_RS25865	768944..769282	+	339	Protein_727	helix-turn-helix domain-containing protein	-
CES85_RS25875	769975..770595	+	621	WP_095448623.1	IS5 family transposase	-
CES85_RS25885	771094..771537	+	444	WP_095448625.1	hypothetical protein	-
CES85_RS25890	771650..772354	-	705	WP_157743525.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	-	1..1032012	1032012

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-95)

Antitoxin

• Ribbon-helix-helix protein, CopG (3-40)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 10894.34 Da
• Isoelectric Point: 8.0534

>T79402 WP_095448619.1 NZ_CP022605:c767224-766931 [[Ochrobactrum] quorumnocens]
VPRVVITESAAQGLERCRRFLIAKSQEAAQRAGNAIQRHLFQLENAADIGRPFPSAPELRELVIPFGDSGYIALYRHETA
ENAVYVLAFRHQREAGY

Nucleotide

• Length: 294 bp

>T79402 NZ_CP022605:c767224-766931 [[Ochrobactrum] quorumnocens]
GTGCCACGAGTAGTTATAACCGAAAGTGCCGCACAAGGTTTGGAACGCTGCCGTCGATTTCTGATTGCCAAATCACAAGA
AGCCGCACAGCGCGCTGGTAATGCGATTCAACGTCACTTGTTCCAACTCGAGAATGCGGCTGATATCGGGCGGCCTTTCC
CCAGTGCGCCGGAGCTGCGGGAGTTGGTGATCCCTTTTGGGGACTCAGGATATATAGCGCTTTATCGTCATGAAACAGCC
GAGAATGCGGTTTATGTGCTCGCGTTCCGACACCAGAGAGAAGCGGGCTACTGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10402.56 Da
• Isoelectric Point: 6.2260

>AT79402 WP_095448620.1 NZ_CP022605:c767484-767212 [[Ochrobactrum] quorumnocens]
MATSLKIDDALKGRVQQLASQRRRSAHWIMLEAIAQYVEREEARESFKQEAIASWASFKETGRHLTGTEVRNWLNNWGTN
DETSVPECHE

Nucleotide

• Length: 273 bp

>AT79402 NZ_CP022605:c767484-767212 [[Ochrobactrum] quorumnocens]
ATGGCCACCTCCCTCAAAATCGATGACGCTCTGAAAGGGCGCGTCCAACAGCTTGCCAGCCAACGCCGTCGGTCGGCGCA
TTGGATCATGCTCGAAGCCATTGCGCAATATGTTGAGCGCGAAGAAGCCCGCGAGAGTTTTAAACAGGAAGCCATTGCTT
CCTGGGCTTCCTTTAAAGAGACGGGTCGCCATCTTACCGGCACAGAAGTCCGTAACTGGCTCAACAACTGGGGCACAAAT
GACGAAACATCGGTGCCAGAGTGCCACGAGTAG