Detailed information of TA system TA079398

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 371710..372257
• Replicon: plasmid unnamed1
• Accession: NZ_CP022605
• Organism: [Ochrobactrum] quorumnocens strain A44

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: CES85_RS23810
• Protein ID: WP_095448303.1
• Coordinates: 371710..372003 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: CES85_RS23815
• Protein ID: WP_095448304.1
• Coordinates: 372003..372257 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CES85_RS23785	367222..368001	+	780	WP_095448300.1	sugar ABC transporter ATP-binding protein	-
CES85_RS23790	368125..368922	+	798	WP_157743498.1	sugar phosphate isomerase/epimerase	-
CES85_RS23800	369512..369729	-	218	Protein_331	IS6 family transposase	-
CES85_RS23805	370004..371545	+	1542	WP_095448302.1	Fic family protein	-
CES85_RS23810	371710..372003	-	294	WP_095448303.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CES85_RS23815	372003..372257	-	255	WP_095448304.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
CES85_RS23820	372538..373845	-	1308	WP_095448305.1	extracellular solute-binding protein	-
CES85_RS23825	373901..374731	-	831	WP_095448306.1	carbohydrate ABC transporter permease	-
CES85_RS23830	374728..375591	-	864	WP_095448307.1	sugar ABC transporter permease	-
CES85_RS23835	375588..376685	-	1098	WP_095448308.1	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	-	1..1032012	1032012
	-	flank	IS/Tn	-	-	369586..369729	143

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-92)

Antitoxin

• Antitoxin ParD (1-76)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11144.81 Da
• Isoelectric Point: 5.5385

>T79398 WP_095448303.1 NZ_CP022605:c372003-371710 [[Ochrobactrum] quorumnocens]
MIFSLSVQAEEDIIAIAEHGIAIFGPIQAKRYHSDLFNTLDLIAKNPQMAREREEISTPVRIHPFKAHLIVYQIEQNGSV
FVLRIRNAFEDWISDPL

Nucleotide

• Length: 294 bp

>T79398 NZ_CP022605:c372003-371710 [[Ochrobactrum] quorumnocens]
ATGATATTCAGTCTCTCAGTTCAGGCGGAAGAAGATATAATTGCTATTGCAGAGCACGGCATAGCAATATTCGGACCTAT
ACAGGCCAAACGATATCATTCGGACCTGTTTAACACGTTGGATCTGATTGCCAAAAATCCACAAATGGCACGCGAACGGG
AAGAAATCTCTACACCTGTTCGTATTCATCCGTTTAAAGCTCATCTAATTGTTTATCAAATCGAACAAAACGGATCCGTA
TTTGTACTTAGGATACGGAATGCATTTGAAGACTGGATTAGCGACCCTCTCTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9500.83 Da
• Isoelectric Point: 10.3104

>AT79398 WP_095448304.1 NZ_CP022605:c372257-372003 [[Ochrobactrum] quorumnocens]
MATMNVSLPHPMKEWVEAQAKTGRYSNVSDYVRDLIRKDQMRGDKIAAMQRFVDDGLQSGKGTRSRDDLFAIAIANAEKS
LKRN

Nucleotide

• Length: 255 bp

>AT79398 NZ_CP022605:c372257-372003 [[Ochrobactrum] quorumnocens]
ATGGCTACGATGAATGTATCGCTCCCTCATCCCATGAAAGAATGGGTTGAGGCGCAGGCCAAAACAGGGCGCTATTCGAA
CGTAAGTGATTATGTGCGCGACTTGATCCGTAAGGATCAGATGCGTGGCGATAAGATCGCAGCAATGCAGCGATTTGTCG
ACGATGGCCTACAAAGTGGCAAGGGAACTCGTTCGCGTGATGATCTCTTCGCTATTGCAATTGCTAACGCGGAAAAATCT
CTGAAACGCAACTAA