Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 331281..331830 Replicon plasmid unnamed1
Accession NZ_CP022605
Organism [Ochrobactrum] quorumnocens strain A44

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CES85_RS23620 Protein ID WP_095448271.1
Coordinates 331281..331565 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CES85_RS23625 Protein ID WP_095448272.1
Coordinates 331558..331830 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CES85_RS23605 326400..328019 - 1620 WP_095448268.1 ABC transporter substrate-binding protein -
CES85_RS23610 328048..330093 - 2046 WP_095448269.1 NADH:flavin oxidoreductase -
CES85_RS23615 330272..331210 + 939 WP_095448270.1 LysR family transcriptional regulator -
CES85_RS23620 331281..331565 - 285 WP_095448271.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CES85_RS23625 331558..331830 - 273 WP_095448272.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CES85_RS23630 331990..332418 - 429 WP_095448273.1 DUF4279 domain-containing protein -
CES85_RS23635 332531..333296 + 766 WP_095448274.1 IS5 family transposase -
CES85_RS23640 333369..334451 + 1083 WP_095448275.1 IS110 family transposase -
CES85_RS23645 334700..336361 - 1662 WP_095448266.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..1032012 1032012
- flank IS/Tn - - 333369..334451 1082


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11073.80 Da        Isoelectric Point: 10.8860

>T79397 WP_095448271.1 NZ_CP022605:c331565-331281 [[Ochrobactrum] quorumnocens]
MTEYSLEFHKAARKEWSKLDANTRKQFAAKLQQRLSNPHVPGDRLSGSRERYKIKLRSIGYRLVYEVLDGRLIVLVLAVG
RRDKSDVYERAHMR

Download         Length: 285 bp

>T79397 NZ_CP022605:c331565-331281 [[Ochrobactrum] quorumnocens]
ATGACTGAATATTCTCTTGAATTTCACAAGGCTGCCCGGAAGGAATGGTCGAAGCTGGACGCCAATACCCGTAAGCAATT
TGCCGCCAAGCTACAGCAAAGACTAAGTAATCCGCATGTTCCCGGAGATCGTCTGAGCGGGAGCAGGGAGCGTTATAAAA
TTAAGCTTCGTAGTATTGGTTACAGACTTGTATATGAAGTGCTGGACGGCAGGTTGATCGTGCTGGTTCTCGCCGTCGGA
CGCCGGGACAAATCTGATGTCTACGAGCGCGCGCATATGCGTTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9770.18 Da        Isoelectric Point: 4.3766

>AT79397 WP_095448272.1 NZ_CP022605:c331830-331558 [[Ochrobactrum] quorumnocens]
MVHIVLSEVTASVSELKKNPMGTVRAGEGAAVAILNRNEPAFYCVPASVYEVMLERLEDAALSKLTDERVADLGKTFKAK
IEDGDIVFDD

Download         Length: 273 bp

>AT79397 NZ_CP022605:c331830-331558 [[Ochrobactrum] quorumnocens]
ATGGTTCACATTGTCCTTTCCGAAGTTACAGCGAGCGTATCGGAGCTCAAGAAAAACCCCATGGGAACAGTTCGGGCTGG
TGAAGGCGCAGCCGTTGCCATCTTAAACCGCAATGAGCCAGCATTTTACTGCGTGCCGGCAAGTGTTTATGAAGTGATGC
TGGAGCGGCTTGAAGATGCGGCTCTCAGCAAGCTGACTGACGAGCGCGTAGCTGATTTAGGCAAAACGTTCAAAGCAAAA
ATCGAAGACGGCGACATTGTCTTCGATGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References