Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4633329..4633474 Replicon chromosome
Accession NZ_CP022573
Organism Klebsiella pneumoniae strain BIC-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4633365..4633467 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4633329..4633474 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHX41_RS23400 4628459..4630519 + 2061 WP_032422099.1 oligopeptidase B -
CHX41_RS23405 4630523..4631182 - 660 WP_002911407.1 exodeoxyribonuclease X -
CHX41_RS23410 4631261..4631491 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CHX41_RS23415 4631604..4631978 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CHX41_RS23420 4631982..4632851 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
CHX41_RS23425 4632868..4633206 + 339 WP_002911404.1 YebY family protein -
- 4633329..4633474 - 146 - - Antitoxin
- 4633365..4633467 + 103 - - Toxin
CHX41_RS28895 4633842..4633985 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CHX41_RS23435 4634090..4635058 - 969 WP_004151446.1 VirK/YbjX family protein -
CHX41_RS23440 4635215..4635868 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
CHX41_RS23445 4635865..4636056 - 192 WP_002911395.1 YebW family protein -
CHX41_RS23450 4636154..4636393 - 240 WP_002911393.1 YebV family protein -
CHX41_RS23455 4636509..4637942 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T79244 NZ_CP022573:4633365-4633467 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT79244 NZ_CP022573:c4633474-4633329 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References