Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4540314..4540830 Replicon chromosome
Accession NZ_CP022562
Organism Pseudomonas monteilii strain B5

Toxin (Protein)


Gene name relE Uniprot ID A0A3G2HKE7
Locus tag CHR29_RS21425 Protein ID WP_016712032.1
Coordinates 4540314..4540601 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A446A2J5
Locus tag CHR29_RS21430 Protein ID WP_028700126.1
Coordinates 4540591..4540830 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHR29_RS21415 4535353..4538232 + 2880 WP_016712029.1 ribonucleoside-diphosphate reductase subunit alpha -
CHR29_RS21420 4538950..4540200 + 1251 WP_016712031.1 ribonucleotide-diphosphate reductase subunit beta -
CHR29_RS21425 4540314..4540601 - 288 WP_016712032.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CHR29_RS21430 4540591..4540830 - 240 WP_028700126.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CHR29_RS21435 4541431..4542669 + 1239 WP_016712034.1 OprD family porin -
CHR29_RS21440 4542833..4543639 + 807 WP_016712035.1 NAD(P)-dependent oxidoreductase -
CHR29_RS21445 4543666..4544547 + 882 WP_016712036.1 SMP-30/gluconolactonase/LRE family protein -
CHR29_RS21450 4544613..4545584 + 972 WP_063977227.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11233.07 Da        Isoelectric Point: 9.9006

>T79223 WP_016712032.1 NZ_CP022562:c4540601-4540314 [Pseudomonas monteilii]
MTYSLDFDCRALKEWKKLGDTVREQFKKKLAEVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIGQEIVVFVVAVDR
RERDQAYKKAAERLE

Download         Length: 288 bp

>T79223 NZ_CP022562:c4540601-4540314 [Pseudomonas monteilii]
ATGACCTATAGCCTCGACTTCGATTGCCGCGCATTGAAAGAGTGGAAGAAGCTGGGCGATACAGTGCGTGAGCAGTTCAA
GAAGAAACTGGCAGAGGTCTTGCTCAATCCTCGAGTCGAGGCAAACCGCCTTCACTCGCTGCCAGATTGCTACAAAATCA
AGCTTCGCAGCAGTGGGTACAGGCTGGTCTATCAGGTCATTGGCCAAGAGATCGTGGTTTTTGTCGTTGCTGTTGATCGC
CGTGAACGGGACCAAGCTTACAAAAAGGCTGCTGAGCGGCTTGAATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9111.46 Da        Isoelectric Point: 4.6310

>AT79223 WP_028700126.1 NZ_CP022562:c4540830-4540591 [Pseudomonas monteilii]
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLASPQRVRVQLDDL

Download         Length: 240 bp

>AT79223 NZ_CP022562:c4540830-4540591 [Pseudomonas monteilii]
ATGGCTTCCATCAATATCCGCGTCGACGACGATCTCAAAGCTCGCGCCTACAAAGAGCTTGAGCGTCTTGGTGTAACCCC
CTCCGAACTCATGCGCCAAGCCCTGCAATATGTAGCTGAGCGGGGCAAGCTACCCTTCCGGCCGGTCCTGATGACCGAGG
AAGATGAAGACCTCATTGCCACTGTACAAGAGAGGCTTGCTTCCCCGCAGCGCGTGAGGGTTCAGCTGGATGACCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2HKE7

Antitoxin

Source ID Structure
AlphaFold DB A0A446A2J5

References