Detailed information of TA system TA079216

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 4191823..4192706
• Replicon: chromosome
• Accession: NZ_CP022560
• Organism: Pseudomonas putida strain B1

Toxin (Protein)

• Gene name: -
• Uniprot ID: R9VG37
• Locus tag: CHR26_RS19840
• Protein ID: WP_016487683.1
• Coordinates: 4192269..4192706 (+)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: R9VFG2
• Locus tag: CHR26_RS19835
• Protein ID: WP_016487684.1
• Coordinates: 4191823..4192272 (+)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHR26_RS30055	4187416..4187553	-	138	WP_157754405.1	hypothetical protein	-
CHR26_RS19810	4187660..4188283	-	624	WP_016487689.1	glutathione S-transferase	-
CHR26_RS19815	4188483..4188782	+	300	WP_016487688.1	DUF3077 domain-containing protein	-
CHR26_RS19820	4188862..4189584	+	723	WP_023047356.1	hypothetical protein	-
CHR26_RS19825	4189877..4190797	+	921	WP_060517273.1	LysR family transcriptional regulator	-
CHR26_RS19830	4190941..4191717	+	777	WP_095115508.1	SDR family oxidoreductase	-
CHR26_RS19835	4191823..4192272	+	450	WP_016487684.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
CHR26_RS19840	4192269..4192706	+	438	WP_016487683.1	RES family NAD+ phosphorylase	Toxin
CHR26_RS19845	4192714..4193868	-	1155	WP_016487682.1	aminotransferase class V-fold PLP-dependent enzyme	-
CHR26_RS19850	4194062..4194988	-	927	WP_060517277.1	LysR family transcriptional regulator	-
CHR26_RS19855	4195128..4196357	+	1230	WP_016487680.1	acyl-CoA dehydrogenase	-
CHR26_RS19860	4196446..4197126	+	681	WP_145914022.1	hypothetical protein	-
CHR26_RS19865	4197128..4197511	+	384	WP_095115706.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-138)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (33-91)

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 16005.35 Da
• Isoelectric Point: 6.2187

>T79216 WP_016487683.1 NZ_CP022560:4192269-4192706 [Pseudomonas putida]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPSGAMLEVLVHLEIDPEDFPTTMRLIRIELPDTVSQAQLPALQ
PGWSAQPELTRALGNRFLDDCSALLLPVPSAIMPSTINYLFNPRHAQAQRAKIQVEDFTPDSRLF

Nucleotide

• Length: 438 bp

>T79216 NZ_CP022560:4192269-4192706 [Pseudomonas putida]
GTGATTTTGTGGCGTATCAGCGCCTATGCAGATTTGAGCGGCACTGGGGGGCTGCGTGTTAGCGGACGCTGGCACCAGGC
GGGCCGGCCCGTGGTGTATGCCGCCACCAGCCCTTCCGGGGCGATGCTCGAGGTGCTTGTGCACCTGGAGATCGACCCAG
AGGATTTTCCTACCACCATGCGCCTGATCCGTATCGAATTGCCTGACACGGTTTCACAGGCGCAGTTGCCCGCCCTGCAG
CCCGGCTGGTCCGCTCAGCCTGAGTTGACCCGGGCGCTGGGCAATCGCTTTCTGGATGACTGCTCGGCTTTACTGCTGCC
CGTGCCGAGCGCGATCATGCCCAGCACCATCAACTACCTGTTCAACCCACGGCACGCGCAGGCACAGCGTGCGAAAATCC
AGGTCGAGGATTTTACCCCGGACAGCCGCTTGTTCTAG

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 17096.64 Da
• Isoelectric Point: 6.1089

>AT79216 WP_016487684.1 NZ_CP022560:4191823-4192272 [Pseudomonas putida]
MLAEVLRDNGYHEYRARLQALLEIPELASDFEIHTRITHGFAATWLVKLTERGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEADKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Nucleotide

• Length: 450 bp

>AT79216 NZ_CP022560:4191823-4192272 [Pseudomonas putida]
ATGCTTGCCGAAGTGCTTCGTGACAACGGTTACCACGAGTACCGGGCGCGCCTGCAGGCGCTGCTGGAAATACCCGAACT
TGCCAGTGACTTCGAAATCCACACCCGGATCACCCACGGTTTTGCCGCTACCTGGCTGGTGAAGCTGACCGAGCGCGGTG
TGTTCACGCCGGTGGAGCGGGACCAGATCATTCCCCTGCGCACCCTGAAAACCCGTATCGAACGTGACCAGCCGCTGACC
GTGGAAGAGAGTGATCGGCTGTTCCGTTCGGCCCACATCACCGCCATGGCCGAAGCCGTGTTTGGCGAGGCGGACAAGGC
CAAGCGCTGGCTGTCCAAGCCCAAGGAACGTTTTTCGGGGCTGACGCCGATGCAGATGCTCACAACCCAGCAAGGCACCA
CTCAGGTCGAAGAGATGCTGCTGCAGATTGCCGAGGGTTTTGGCCTGTGA

Structures

Toxin

• AlphaFold DB: R9VG37

Antitoxin

• AlphaFold DB: R9VFG2