79211

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 995365..995881 Replicon chromosome
Accession NZ_CP022560
Organism Pseudomonas putida strain B1

Toxin (Protein)


Gene name relE Uniprot ID A0A1I5YE31
Locus tag CHR26_RS04735 Protein ID WP_074918669.1
Coordinates 995365..995646 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A482UCX2
Locus tag CHR26_RS04740 Protein ID WP_033942931.1
Coordinates 995636..995881 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHR26_RS04710 991177..991449 + 273 WP_174892493.1 hypothetical protein -
CHR26_RS04715 991547..992515 + 969 WP_074918677.1 DUF932 domain-containing protein -
CHR26_RS04720 992596..993600 + 1005 WP_121412243.1 YqaJ viral recombinase family protein -
CHR26_RS04725 993692..994642 + 951 WP_121412242.1 hydrolase or metal-binding protein -
CHR26_RS04730 994614..995111 + 498 WP_074918671.1 DNA repair protein RadC -
CHR26_RS29930 995122..995295 + 174 WP_009686156.1 hypothetical protein -
CHR26_RS04735 995365..995646 - 282 WP_074918669.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CHR26_RS04740 995636..995881 - 246 WP_033942931.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CHR26_RS04745 996066..996791 - 726 WP_034019520.1 inovirus Gp2 family protein -
CHR26_RS04750 997269..997499 - 231 WP_034019465.1 AlpA family transcriptional regulator -
CHR26_RS04755 997569..998873 - 1305 WP_145913410.1 hypothetical protein -
CHR26_RS04760 999108..999782 + 675 WP_034019461.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10763.64 Da        Isoelectric Point: 10.7574

>T79211 WP_074918669.1 NZ_CP022560:c995646-995365 [Pseudomonas putida]
MTYKLEFLPSALKEWEKLGHTVREQAKKKLRERLEAPKVQADALRDLPGHYKIKLRTAGYRLVYRVEDDRVVVIVVAVGK
RERSAAYKAAGKR

Download         Length: 282 bp

>T79211 NZ_CP022560:c995646-995365 [Pseudomonas putida]
ATGACCTATAAGCTCGAGTTCCTGCCCTCAGCGCTGAAGGAATGGGAGAAGCTGGGTCATACAGTGCGTGAGCAGGCAAA
GAAAAAACTGCGTGAGCGGCTGGAAGCACCAAAGGTACAGGCTGATGCCCTCAGGGATCTGCCTGGGCACTACAAGATCA
AGCTCCGAACAGCAGGCTATCGTTTGGTGTATCGGGTCGAAGATGATCGGGTGGTTGTGATTGTGGTCGCAGTGGGCAAG
CGTGAACGAAGTGCAGCTTACAAGGCAGCAGGTAAGCGTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8653.98 Da        Isoelectric Point: 4.1469

>AT79211 WP_033942931.1 NZ_CP022560:c995881-995636 [Pseudomonas putida]
MQSVLADVAVSVSELKKNPTGVMAGAGGMPVAVLNHNRVMGYMVPAELYEQMLDRLDDLDLIDVVNARSGEKGVPVNLDD
L

Download         Length: 246 bp

>AT79211 NZ_CP022560:c995881-995636 [Pseudomonas putida]
ATGCAGAGTGTTTTGGCTGACGTTGCAGTGAGCGTTTCTGAGCTGAAGAAAAACCCCACCGGTGTTATGGCTGGTGCTGG
TGGCATGCCGGTCGCCGTTCTCAATCATAACCGCGTGATGGGGTACATGGTGCCAGCCGAGCTGTACGAGCAGATGCTGG
ACCGTCTGGACGATCTGGATCTGATCGATGTCGTTAATGCACGCTCCGGTGAGAAGGGGGTGCCGGTGAACCTGGATGAC
CTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1I5YE31

Antitoxin

Source ID Structure
AlphaFold DB A0A482UCX2

References